Location: Cambridge, MA
Company: Pfizer Belgium
antibody drugs. Our patented Helicon peptide technology allows us to modulate the activity of well-known intracellular disease drivers that have thus far evaded small molecule and biologic therapies. Fog Pharma's lead program targets ---Catenin, an oncogenic driver in the WNT pathway.
Inhibition of ---Catenin has the potential to benefit 10-15% of all cancer patients, and is just one of many opportunities for Fog's lead-discovery platform to change future medicines, therapies and lives. Our Phase 1 clinical trial has been initiated for this program. What's the opportunity? As a Process Chemist at Fog Pharma, you will partner with scientists across the organization to discover and develop
the best Helicon TM peptides and tailor them to fit patients' needs. We are looking for an enthusiastic and innovative Process Chemist to join a multidisciplinary team and help us discover and develop novel inhibitors of undruggable disease targets.
Your role will report to the Vice President of medical Development and will be to establish robust manufacturing processes for our drug substance. This will require both hands-on and strategic approaches, leveraging internal and external capabilities with high flexibility. Ideal candidates will be experienced, energetic, and passionate, with a broad knowledge of Process Chemistry / Chemical Development to influence and guide the best route
selection and development of our chemical processes. This position is primarily lab-based, and you will be a primary data generator with opportunities to lead a subteam of process chemists.
Leverage internal and external capabilities to advance our programs. Lead by example and take a hands-on approach to solving our most pressing challenges. Lead a subteam of 1-2 process chemists. Partner with early discovery through late stage development to discover and implement the best synthetic approaches to our Helicon TM peptides. Develop the best strategy for the synthesis of our Helicon TM peptides. What you'll need to be successful: Ph D with a minimum of 6-8+ years of industry experience in process chemistry.
Experience with development of safe, scalable processes and technology transfer to manufacturing sites. Hands-on experience with kilo-lab deliveries is a plus. Excellent communication, organization, strategic, and cross-functional team skills. Experience directly managing external vendors is a plus. Experience with Quality Assurance, Quality systems, and GMP production is a plus. Experience with regulatory filings is a plus. Synthetic experience with peptides is a plus. Able to work on-site and attend in-person meetings (Fog employees are required to be fully vaccinated to attend in-person work-related activities.
Reasonable Accommodations will be made for individuals with a sincerely held religious belief or disability who are not vaccinated) As an equal opportunity employer, Fog values diversity and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, interaction, interactionual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. 30 Acorn Park Drive - Cambridge, MA 02140 - #J-18808-Ljbffr
collaboration focused on the development of novel protocols for the differentiation of induced pluripotent stem cells (i PSC) into terminal cell types suitable for cell-based therapies. Works closely with a cross-disciplinary team of biologists and bioinformatic scientists to apply novel computational techniques. #J-18808-Ljbffr
medicines to patients with rare genetic cardiomyopathies. We are looking for a candidate with a background in cellular and molecular biology. In this role, you will be mainly responsible for developing and implementing a range of molecular and functional assays to backss the disease process, discover new medicines, and evaluate their therapeutic potential using human induced pluripotent stem cell derived cardiomyocytes (Hi PSC-CMs).
Additionally, you will be part of cross-functional teams and state of the art technology cores, and your scientific contributions will help advance Alexion's preclinical programs to the clinic. You will be responsible for: Developing and characterizing induced
pluripotent stem cell lines that carry disease-relevant mutations. Differentiation of these lines into cardiomyocytes. Development and implementation of molecular and functional assays that capture aspects of the disease phenotype associated with the relevant mutations.
Ultimately, these assays will be used to evaluate novel genomic medicine therapeutics. Collaborating within multi-functional teams pursuing both in vitro and in vivo (mammalian) work. Documenting experimental design and results in an electronic lab notebook. Presenting data to the team, unit, or external stakeholders. Keeping abreast of recent advancements in scientific literature. You will need to have: Bachelor's degree
in Biology (or equivalent) with 3+ years of working experience in academia or industry Master's degree in Biology (or equivalent) with 1-2 years of working experience in academia or industry Experience designing and optimizing molecular and immunoassays including dd PCR, RT-q PCR, Western blot, ELISA, MSD, and flow cytometry.
Proficiency with mammalian cell culture, transfection, and gene delivery including AAV, lentivirus, and adenovirus. Use of scientific databases and applications for data management and analysis (Microsoft Office 365, Graph Pad Prism, Soft Max Pro, Flow Jo). Collaborate with team members across disciplines to support portfolio. Maintain a detailed, contemporaneous record of experiments and results in accordance with company standards.
Strong attention to detail, critical thinking skills, ability to multitask and prioritize activities, and effective written and verbal communication skills. We would prefer for you to have: Experience with culturing i PSCs or engineering cell lines. Experience with functional live cell readouts. In vivo experience including rodent handling, dosing, ex vivo tissue processing, and histology. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines.
In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law. Astra Zeneca embraces diversity and equality of opportunity.
We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. #LI-EB1 #LI-HYBRID
including 105A CMR 725 and 935 CMR 500. The Retail Associate position is designed to provide the people that we serve with a consultative buying experience to consistently provide a transformative guest experience by making every effort to partner with each guest to find the best available.
Responsibilities: Assist qualifying patients and caregivers and adult use guests in obtaining their cannabis/cannabis infused or medicated products Participate actively in ongoing training in customer service delivery Assist with dispensary opening and closing, to include the protection of dispensary assets by following Temescal Wellness operational policies and procedures Compliance with program regulations
as they relate to retail operations and to the dispensing of medicated products, including the use of seed to sale software Maintenance of a well-stocked and beautifully merchandised dispensary Uphold all standards pertaining to dispensary cleanliness and Serv-Safe for infused product handling Consistently provide a transformative guest experience by making every effort to partner with the guest to find the best available product for their stated need Maintain store security, including building security and the security of all company assets to include the handling of cash and other financial instruments All other duties assigned by management This job posting is intended to describe the general
requirements for the performance of this role.
It is not a complete statement of duties, responsibilities or requirements. The role of the PSA will expand and evolve based upon the needs of the organization and the demands of our guests. Requirements: Authentic passion to serve the qualifying patients and caregivers of the state of Massachusetts, as well as adult use guests Affinity for handling multiple demands simultaneously and proficiency with time management Ability to learn and to use seed to sale POS software in compliance with program regulations Strong attention to detail High-energy, enthusiasm and positivity, a general can-do spirit Exemplary customer service skills as observed by supervisors and as validated by guest and patient feedback Ability to actively listen to guests and to assist in guiding their product choices.
Thorough knowledge of all program guidelines and relevant Temescal Wellness policies and procedures Strong verbal and written communication skills Ability to visually examine products for quality and signage/labeling accuracy Exhibit a " can-do" attitude and a willingness to take on new responsibilities and tasks as they become necessary Ability to assure compliance by demonstrating attention to detail and the aptitude to process and internalize a large volume of information, most specifically around state regulations Relentless pursuit of accuracy and of achieving efficiency through technology and scalable processes Bilingual in English/Spanish or English/Portuguese is a plus Essential Job Functions: Ability to stand and walk for extended periods of time Bend and stoop to grasp objects, bend and twist neck and waist, reach above and below shoulders and squat Bend and lift loads, not to exceed 50 pounds Repetitive use of hands for grasping, pushing, pulling and fine manipulation Compensation and Benefits: Starting wage: $17.00 - $18.00 per hour Employer pays approximately 70% of medical, dental and vision insurance, including for family members Generous time off policy Mission-driven organization with an excellent work-life balance This position is not eligible for visa sponsorship.
Temescal Wellness is committed to creating a diverse environment and is proud to be an Equal Opportunity Employer. We are committed to fair hiring practices and to creating a welcoming environment for all team members. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, interactionual orientation, national origin, genetics, disability, age, or veteran status.
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Boston, Massachusetts, this law firm focuses on biotechnology, chemistry, and medicine to deal with complex issues of intellectual property. The firm also focuses particularly on technology licensing, patent prosecution, corporate and investment diligence, patent portfolio management, and freedom-to-operate analysis.
This firm has represented different types of clients including medical centers, universities, and all sizes of corporations. This firm represents clients in technological innovation and scientific discovery. Additional Skills: The candidate should possess excellent analytical and communications skills; must think, write, and speak clearly.
The optimal project outcome will see the new assay(s) implemented in Selux's second-generation AST platform in addition to publications. The successful candidate will work closely with Selux's senior scientists and engineers, have direct access to Selux's esteemed scientific and clinical advisors, and build industry and academic partnerships necessary to make the project successful.
We are looking for a candidate with experience working with bacteria and assay development, including use of time-resolved Forster resonance energy transfer (TR-FRET), fluorescence polarization/anisotropy. Selux Diagnostics' platforms will enable clinicians to administer personalized therapies to Infectious
Diseases patients within hours rather than days. These advances promise to improve patient care, shorten hospital stays, and combat the growing antibiotic resistance epidemic.
Selux's NGP AST platform offers uncompromised accuracy and an unprecedented speed to results and breadth of menu. The company's Grow-on-the-Go Blood Culture system completes the microbiology laboratory transformation by slashing the time to culture positivity for all samples and incubation during sample transport for integrated health networks. The 35-person company is funded with a combination of Federal and private investment and will begin FDA trials on its initial NGP AST product in this quarter (Q1-2020). The
ideal candidate will have/be: A Ph D in Microbiology, Biochemistry, Molecular Biology, Biomedical Engineering or a related field Experience performing phenotypic assays on bacteria Experience working with a variety of bacterial species Experience developing no-wash assays Experience performing TR-FRET and/or fluorescence polarization A desire to learn industrial R&D and see his/her work come to fruition in a product A desire to continue publishing An independent thinker and problem-solver, who is an enthusiastic and collaborative professional Excellent written and oral communication skills and proven ability to work well in a team environment Passion about an early-stage start-up that aims to change industry and how healthcare is delivered!
recblid 30k3bj2puip0ojss7rrj9os3kdftk0 Ph. D.
