investigators in the department and across the hospital and is responsible for cloning, construct optimization, protein purification, biophysical studies, and structure determination. This job is a bench-based scientist role where you will conduct experiments, interact closely with other scientists and investigators, and participate in collaborative research toward understanding the basis of disease.
Responsibilities : The candidate will use their molecular biology, biochemistry, and structural biology skills, design constructs, and purify proteins for structural and biophysical studies. Work with several labs and determine structures using x-ray crystallography and/or cryo-EM technologies.
Able to troubleshoot cloning, protein expression and purification problems. Interpret, analyze, and communicate structural biology results with collaborators.
Prioritize work and complete assignments in a timely fashion. Train and mentor research associates, students, and/or postdoctoral associates who seek to leverage the Protein Technologies Center's capabilities at St. Jude. Preferred Experience and Skills : Experience in sample preparation for both negative-stain and single particle EM, data collection, data processing and model building. Demonstrated ability to purify challenging macromolecules and/or complexes (e. g. membrane proteins, viral glycoproteins, antibody-antigen complexes
etc. ). Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required.
Ph D in molecular biology, biochemistry, protein engineering, or any related discipline preferred. Minimum Experience: Seven (7) years of relevant post-degree work experience is required with a Bachelor's degree. Five (5) years of relevant post-degree work experience is required with a Master's degree. Three (3) years of relevant post-degree work experience is required with a Ph D. St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay.
Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive.
View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. Other Information St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St.
Jude.
