areas where we believe we can really change the course of medicine and bring big new ideas to life. Astra Zeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death.
This Opportunity We are seeking a highly motivated and independent Senior Scientist with experience in radiomedical development to join our radioconjugate (RC) portfolio team within the Early Oncology Discovery group in Gaithersburg, MD USA. Requisites for this role include a proven track record of scientific excellence and several years of project leadership experience. As a
Senior Scientist in our group, you will be the tumor biology lead for emerging RC portfolio projects, working both with our internal project teams and with external partners to develop novel targeted alpha therapies.
As a core project lead, you will leverage your theoretical and practical expertise to deliver pre-clinical datasets, synthesize cross-functional learnings, establish program priorities, and advance the project through all stages of pre-clinical development. You will represent the project team in front of governance committees and will present program updates at other internal forums. In addition to your individual project leadership responsibilities, you will also provide
intellectual contributions and cross-functional support to RC teams across the portfolio.
Main Duties and Responsibilities You will be expected to serve as the tumor biology lead for one or more radioconjugate programs, working collaboratively with internal cross-functional teams and external partners to ensure the timely generation and dissemination of critical program data to enable project milestone decisions. As a highly organized, self-motivated individual with a strong background in cancer research and radiobiology, you will stay up to date with relevant technical, intellectual, and scientific expertise in tumor biology and cancer modelling, particularly as it relates to targeted radioconjugates, and have a genuine passion for this field of research.
Essential Requirements Ph D Degree with 0-3 years of experience, Master's Degree with 3+ years of experience, or a Bachelor's degree with 7+ years and project leadership experience in a relevant field related to tumor and radiation biology. Expertise in targeted radiomedical therapies, with broad knowledge of the field, is required for consideration of the candidate. Demonstrated ability to lead cross functional project teams. Solid understanding of radiation biology, cell biology, and/or biochemistry in the context of cancer, with a robust desire for continued learning.
Excellent communication, presentation, and interpersonal skills evidenced by a history of successful project delivery in team-oriented, collaborative environments. A consistent track record of productivity, as demonstrated by scientific publications in high quality peer-reviewed journals. Ensures own work, and work of peers, is compliant with Good Laboratory Practice, Safety, Health, and Environment standards and all other relevant internal Astra Zeneca standards and external regulations. Desirable Requirements Prior experience in the biomedical industry and familiarity handling data delivery through contract research organizations preferable but not required.
Direct, hands-on experience in residualization & saturation binding assays, PET-CT imaging, biodistribution studies, non-clinical dosimetry, and other pre-clinical radioimmunoconjugate methods is highly desirable. Experience with targeted alpha emitter therapeutics would be considered favorably. About Our Gaithersburg Oncology Hub Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC.
This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration. The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more.
This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. So, what's next- Are you already envisioning yourself joining our team? Good! We can't wait to hear from you! If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner. Competitive remuneration and benefits apply We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.
Where can I find out more- Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.
We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Date Posted 02-Nov-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity.
We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e. g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.
Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person. About Astra Zeneca in Gaithersburg, MD: Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world.
This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees
benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy.
This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. Summary of the group: The m RNA Drug Product Development Team is a part of the Dosage Form Design and Development group of Biomedical Development.
The team's purpose is to advance the development of m RNA products and processes, including manufacturing of lipid nanoparticles (LNPs) to deliver life-changing vaccines and medicines to our patients.
This purpose is realized through an application of a wide range of scientific disciplines converging to bridge between formulation and device capabilities and providing leadership from early research through CMC activities for m RNA delivery technologies. Areas of focus include: Strong collaboration with medical Sciences Advanced Drug Delivery team to enable identification and selection of appropriate lipids and LNP composition for downstream development activities Lead CMC activities across Dosage Form Design and Development to enable optimization of m RNA-LNPs towards an optimized platform state Advancement of formulation science as it pertains to stabilization of m RNA-LNPs Identification of new technologies to employ for product and process understanding Identification and initiation of key collaborations to advance m RNA-LNP platform development and product understanding both internally and externally Strategic insight for Technology Development in Dosage Form Design and Development Main Duties & Responsibilities: Serve as a key collaborator and partner for advancement of lipid selection and LNP composition with internal Advanced Drug Delivery team Serve as a leader in CMC Drug Product activities for Astra Zeneca m RNA programs providing oversight and execution of all elements of CMC delivery post Lead Optimization through clinical trials.
Lead the development of customized drug delivery formulations for non-viral delivery of various nucleic acids as needed to support therapeutic areas Provide technical expertise, design and execute experiments, analyze and present experimental data and sound recommendations Act as SME in project teams and across the organization Identification and evaluation of external technologies to support advancement of Astra Zeneca's internal m RNA-LNP manufacturing platform Education & Experience Requirements: Ph.
D. degree in a relevant discipline (such as Biopharmaceutics, Pharmaceutics, Chemical Engineering, or Drug Delivery) with 5+ years of relevant industry experience Required Skills: Good understanding/knowledge of the overall drug development process and knowledge of CMC attributes that define formulation robustness. Relevant industrial experience within drug delivery formulations for nucleic acid delivery (nanoparticle delivery technologies)Practical experience with nanoparticle formulation using various fabrication processes, analytical characterization and accurate data reporting Relevant experience with end-to-end nanoparticle and microparticle production processes for encapsulation of nucleic acids and biologics Flexibility and the ability to adjust to changing priorities and operate in a fast-paced industry environment.
Excellent oral and written communication skills; experience working in multidisciplinary teams Desired Skills: Leadership and stakeholder management skills Ability to navigate ambiguity and synthesize actionable next steps to move programs and strategies forward Track record of scientific competence in terms of publications, presentations and networking activities When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines.
In-person working gives us the platform to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.
Join us in our unique and ambitious world. " Why Astra Zeneca? At Astra Zeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-medical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together.
Interested? Come and join our journey. So, what's next! Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it's yours. Where can I find out more? Check out our landing page for more information on our BPD group careers. /bpd Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Date Posted 07-Nov-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity.
We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e. g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.
Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
Astra Zeneca is a global, science-led, patient-focused biomedical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading medical companies.
At AZ, we're proud to have an exceptional workplace culture that encourages innovation and collaboration. Here, employees are empowered to express different perspectives - and made to feel valued, energized and rewarded for their ideas and creativity. AZ is a place where passionate people can immerse themselves in their work and make significant contributions to scientific excellence and medicines - does this describe
a place where you would like to work? At Astra Zeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.
We're passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life! Astra Zeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer and to ultimately eliminate cancer as a cause of death! What you'll do: We are seeking a computational
chemist for our Oncology medicinal chemistry department based in Waltham, Massachusetts.
The successful candidate will be a professional computational chemist, with a passion for drug discovery and ideally experience of working in drug discovery project teams within a biotech or medical setting. You will be working closely with an established, transnational team of computational chemists within Astra Zeneca working on oncology drug discovery projects across a range of modalities and will have access to innovative computational methods, such as our FEP and AI platforms, and excellent lead generation capabilities. Major Responsibilities: As a leading member of the medicinal chemistry design team, you will be responsible for: Setting and delivering on computational and medicinal chemistry strategies to impact project success at all stages from drug target identification through to clinical candidate nomination.
You will have accountability for setting the computational chemistry strategy, carrying out structure- and ligand-based design and data analysis, extracting insight from large proprietary structural biology and SAR data sets; your contributions to molecular design will be expected to result in inventorship on patent applications. You will work closely with scientists from other disciplines including structural biology, biophysics, ADME/DMPK and safety sciences as part of the wider drug discovery project team and will present your work regularly to peers and senior partners.
Depending on experience and interest, you might also function as the lead chemist for a drug discovery project. At Astra Zeneca, we value scientific innovation. Maintaining an awareness of the current state-of-the art, you will identify promising new computational methodologies or technologies that could benefit drug discovery and will develop and implement these through internal or external collaborations, sharing exemplary practice across Astra Zeneca.
You will be expected to publish your work regularly in high quality scientific journals and at national and international conferences. You'll have the opportunity to build academic collaborations and to supervise graduate scientists and postdocs, as well as to mentor colleagues. The scope for personal development is vast. Education, Qualifications, Skills and Experience: Requirements: Ph. D. degree in computational chemistry (or similar), ideally with greater than 5 years of experience working as a computational chemist on drug discovery projects in a medical or Biotech setting, or B.
Sc. /M. Sc with 10+ years of experience Broad experience in protein structure and dynamics, structure- and ligand-based design, data analysis and/or property prediction A passion for drug discovery and an excellent understanding of medicinal chemistry concepts Innovative problem-solver, with a track record of impacting drug project delivery Scientific and project impact exemplified by high quality scientific publications Strong oral and written communication skills, team-working and time-management skills Why Astra Zeneca?
At Astra Zeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-medical company can be. This means we're opening new ways to work, pioneering innovative methods and bringing unexpected teams together. Interested? Come and join our journey. Site Description: Our Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park Bio Hub, just west of the city center.
Our Bio Hub facility, is a bold new R&D initiative, which cultivates life science discoveries and the exchange of ideas. Here, we play host to some of the most ground breaking technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to crafting a culture of inclusion and collaboration.
With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers. Our Waltham site offers a variety of amenities to help book efficiency and help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, & full-service cafeteria. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while growing collaboration between teams and the greater research community. So, what's next?
A place built on courage, curiosity, and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take calculated risks that write the next chapter for our pipeline. If you are swift to action, confident to lead, willing to collaborate, and passionate about the possibilities, then we are keen to hear from you! Where can I find out more? Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Next steps : Apply today, or connect with our Talent Acquisition Partner - Kayla Harris: /in/kayla-harris-8723ab13b/ for a confidential discussion to explore this opportunity further.
We are looking forward to hearing from you! Date Posted 13-Nov-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e.
g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
We currently have an exciting opportunity for someone who has a passion for PKPD modeling and DMPK science, applied to Cancer biology, ideally with experience of working with large molecule drug projects to join our team. As a Senior Scientist Translational PKPD, you will have the opportunity to drive strategy and provide global leadership in PKPD science on Antibody drug conjugates and Radio immuno- conjugates.
Your day-to-day role is to provide projects with specialist modeling input into exploring the PK/PD/Efficacy in pre-clinical models, and using these models in order to iteratively build an understanding of the dose & schedule requirements for therapeutic intervention across different
patient populations as a single agent and combined with other agents. Accountabilities: Representing Translational PKPD group and providing overall scientific leadership for cross functional and external collaborations involving DMPK.
Exploring the effects on target and pathway to understand the requirements for efficacy and set a candidate drug target profile (CDTP). Predicting human dose and regimen together with providing input into exposure and pharmacodynamic (PD) biomarker based decision criteria for early clinical trials. Driving learning through back translation of early clinical exposure and PD data and providing prioritized future options for clinical testing. Leading and participating
in Oncology strategic scientific initiatives and continuous improvement projects by providing expert M&S knowledge.
Having a breadth of influence and impact across Astra Zeneca Clinical Pharmacology and externally within their discipline. Identifying, championing and developing new insights. Leading scientific discipline networks and acting as a focus for debate within the Astra Zeneca scientific community. Advising on and participating in the development of Discovery or Development strategies in PKPD. Managing student and Post Doc programmes. Leading external collaborative projects with academic or cross-pharma pre-competitive groups. Providing disciplinary scientific leadership and presenting work through patents, publications and lectures.
Requirements: Education: Ph D, Completing Ph D before start date of position (preferably February 2024), Masters with at least 3 years of experience, or equivalent degree in a field with a significant component of Modeling & Simulation, such as systems biology, quantitative pharmacology, pharmacometrics, chemical engineering, physics, medical sciences or applied mathematics. 0-4 years of experience in a subject area with a significant component of Modeling & Simulation, such as systems biology, quantitative pharmacology, pharmacometrics, chemical engineering, physics, medical sciences or applied mathematics.
Desirable Experience: Relevant industry experience in Modeling & Simulation, ideally in preclinical/translational setting with a focus on ADC or RIC, or a MS degree with proven industry experience. Experience in a project-facing role within medical R&D. Comprehensive understanding of DMPK and pharmacology/safety aspects of drug discovery and development with a strong publication record. Track record of supporting PK, PKPD and TKPD aspects of projects, with a delivery focus and ability to meet timelines to prespecified quality and cost.
Specialist in tools such as Win Non Lin/Phoenix NLME, Non Mem, Berkeley Madonna, MATLAB, and Sim CYP. Excellent interpersonal and communication skills coupled with strong influence and leadership skills. Providing disciplinary scientific leadership and presenting work through patents, publications and lectures. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions.
That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. At Astra Zeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science.
Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. Empowered to step up, we free ourselves from fear of failure to dig deep into the biology of complex diseases and make bold decisions. Celebrating our successes and failures along the way. Are you ready to embrace new and varied opportunities to develop and learn? Are you ready to be part of a team that makes a bigger impact on patients' lives?
If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. Apply now! Date Posted 06-Dec-2023 Closing Date 05-Feb-2024Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e.
g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
to the advancement of innovative Cell Therapy products by designing and conducting laboratory experiments, developing methodology, and generating and interpreting scientific data in a highly collaborative environment. Accountabilities: As a Scientist, Bioscience, you will conduct hands-on primary cell culturing, immune functional assays and phenotyping.
You will manipulate and characterize primary cells and cell lines, contribute to experimental plans and designs, backss and report data with high integrity, and communicate results to manager and team members. You will also support a team and work collaboratively with project managers to ensure the efficient relay of information and forward
translation of data. Essential Skills/Experience: BS/MS in a relevant scientific field and 3+ years of research experience in molecular and cellular biology of T and NK lymphocytes, cancer biology, tumor microenvironment, or related field Hands-on experience in the cell culture of established cell lines and/or primary human immune cells Basic expertise on flow cytometry acquisition and analysis In vivo experience with different mouse models Desirable Skills/Experience: Previous experience in the development of CAR-T cells, TCR-T cells, etc.
Familiarity with gene editing techniques (e. g. CRISPR/Cas, viral engineering, base editing, etc. ) Biotechnology or medical industry experience preferred.
Hands-on experience in in vitro NK/T-cell functional characterization including in vitro cytotoxicity assays, proliferation, cytokine measurement.
At Astra Zeneca, we are on a mission to eliminate cancer as a cause of death. As part of our Oncology R&D team, you will be at the forefront of applying science to studies and using innovative approaches to create new possibilities. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. Our commitment to patients and pioneering spirit are truly embedded and it's what makes our pipeline unique.
About Our Gaithersburg Oncology Hub Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration. The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy.
This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. Ready to make a difference? Apply now and join us in our mission to eliminate cancer as a cause of death. Please contact Bobbi Poole, our Talent Acquisition Partner. Closing Date: January 5, 2024 Competitive remuneration and benefits apply We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive.
We have a generous paid time off program and a comprehensive benefits package. Where can I find out more- Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.
We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
Please contact us to request accommodation. Date Posted 07-Dec-2023 Closing Date 04-Jan-2024Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e.
g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
of progenitor cell populations that includes but is not limited to pre-Malignancy/Multiple Myeloma. These efforts will support the generation of compelling preclinical data packages with an opportunity to participate in a wide range of drug discovery projects and collaborate with scientists across multiple disciplines.
Astra Zeneca is a global, science-led, patient-focused biomedical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. We are more than one of the world's leading medical companies. Astra Zeneca has a multifaceted environment that cultivates collaboration and innovation. We attract
top minds, and we nurture and build talent. Within Hematology R&D, we are committed to advancing the science to deliver life-changing medicines to patients most in need.
With a combination-focused pipeline that exploits the power of multiple scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. This unit has responsibility for the value chain from discovery through to late-stage development,
enabling rapid acceleration of promising early-stage assets and life-cycle management programs.
Major Responsibilities-Lead efforts to identify and validate hematological targets with a focus on pre malignancy. Generation of suitable models including engineered cell lines and PDX ex vivo models Design and execution of in vivo/ in vitro studies to support the characterization and development of candidate molecules. Genetic manipulation of cells utilizing knockdown or knockout and overexpression of protein for target validation Capable of interrogating and hypothesis generation from single cell and other omic data. Analyze data and maintain clear experimental records.
Adept at managing multiple priorities in an efficient and organized manner. Using decision making, organizational and communications skills to effectively collaborate with biologist and other scientist from a variety of backgrounds. Documentation and presentation of data, findings and experimental conclusions at various meetings including project team and department meetings. Requirements-PHD in biochemistry, cell/molecular biology, genetics, pharmacology, or cancer biology with at least +5 years of experience; industry experience or academic leadership preferred with a commensurate publication record is required.
Familiarity with multiple assay platforms and technologies including single cell analysis. Knowledge and experience with hematological cancers (Multiple Myeloma and NHL). Proven track record of success within project teams, including the ability to prioritize, backss, and either continue or adapt projects. Excellent oral and written communication skillinteractioncellent interpersonal and collaborative skills, and the ability to work independently and effectively in a highly dynamic environment. Ability to build and execute a project plan with defined timelines.
Proven track record of technical proficiency and creativity in experimental design, and independent thinking to achieve short/long-term goals are preferred. Our Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park Bio Hub, just west of the city center. Our Bio Hub facility, is a bold new R&D initiative, which fosters life science discoveries and the exchange of ideas. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science.
We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers. Our Waltham site offers a variety of amenities help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams and the greater research community.
As Astra Zeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026. Find out more information here: Kendall Square Press Release Working at Astra Zeneca Here you'll have the chance to create a substantial difference to patients' lives! With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines - for the world's most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and crafting the patient ecosystem.
Next Steps? Apply now! Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Date Posted 20-Dec-2023 Closing Date 19-Jan-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at Astra Zeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
and Experimental Medicine (TSEM) department in the Respiratory and Immunology therapeutic area. As a department we promote an open and collaborative atmosphere, with a culture that is both science-based and patient-focused. Our mission is to understand disease mechanisms at the molecular level, identify the most effective targets and the right patient populations.
This role is located at one of our sites in either Gothenburg (Sweden) or Gaithersburg (US). Be encouraged and supported to think creatively in our dynamic environment. Here we are free from fear of failure, free to ask the right questions and make bold decisions. We harness data science & AI to fast-forward our research. Making
sure work born in a lab can make a real difference, every day, impacting patients' lives across the world. What you will do In this role, you will work in a highly cross-functional and thriving environment together with specialists in sequencing, immunological and respiratory disease, as well as with other data science & bioinformatics experts.
For this role we are looking for an outstanding bioinformatician to enable translational science via integration of large-scale omics, clinical data, real world evidence and literature data to deliver precision medicine within our pipeline. Youll be identifying novel targets, biomarkers and patient sub-groups through innovative data analysis approaches
including utilization of clinical cohort omics data sets.
You will contribute to the identification of transformational precision medicine propositions to deliver life changing medicines to patients. You will be responsible for planning, performing and interpreting your analysis and communicate results. By applying state-of-the-art analytical methods, you will maximise the knowledge extrapolated from our growing omics data in complex diseases impacting the project progression and future treatment options for patients with unmet medical needs. Depending on your previous experience, your initial career level will be an Associate Principal Scientist or Senior Scientist.
Essential for the role MSc with extensive industry experience, or preferably, Ph D or equivalent in bioinformatics, data science, statistics, biostatistics, mathematics, or another similar subject area. Experience and proficiency in large-scale omics data analysis, integration and interpretation is a requirement. Omics include transcriptomics, single cell, proteomics (Olink, LC/MS), genomics, and other types of next generation sequencing (NGS) such as chromatin state approaches. Excellent coding skills in Python, R, or similar language appropriate for large scale omics analysis and experience with version control (Git/Bitbucket).
A good understanding of life sciences and how omics data can be utilised to derive biological insight will be a minimum requirement. Experience from applying this across different phases of medical discovery and development is a preference. Outstanding communication and collaboration skills, both with experts and non-experts, and with peers as well as stakeholders is expected. Our team is a collaborative group, so the ability to be comfortable working in a goal-oriented way, with a team focused approach is central to be successful in the role.
We believe you also have a high degree of independence and a proactive and delivery focused approach. Desirable for the role Experience in medical R&D and/or Post-doc experience. Molecular understanding of human diseases, patient stratification and biomarker-based endpoint generation, preferentially in respiratory and immunological disorders. Track record of applying bioinformatic analysis to drive projects in drug discovery or development in an industrial or academic setting. Broad experience applying machine learning methods such as random forests, clustering, dimensionality reduction in a systems biology or systems medicine context.
Working in a Linux environment, ideally with experience of cluster or cloud computing (e. g. AWS or Azure). Experience from leading projects with internal groups/external collaborators. Experience working within cross-functional teams. Why Astra Zeneca? At Astra Zeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.
Work policy When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. What's next?
If you are ready to make a difference - apply today, and we'll make it happen together! We welcome your application (including CV and cover letter), no later than January 12, 2024. If you're curious to know more about the position, please get in touch with hiring manager Greet De Baets at xyz X@. Where can I find out more? Follow Astra Zeneca on Linked In: /company/1603/Follow Astra Zeneca on Instagram: /astrazeneca_careers/? hl=en Read more about Biomedicals R&D: /r-d. html Date Posted 20-dec. -2023 Closing Date 19-dec. -2023Our mission is to build an inclusive and equitable environment.
We want people to feel they belong at Astra Zeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
a cure. The Oncology Outcomes Research (O2R) team is composed of high functioning individuals with outstanding strategic, technical and communication skills. The team is a key member of the Evidence Generation and External Alliances Organization within the Global Medical function and develops strategy for and delivers impactful real world, economic and patient reported research for the AZ oncology portfolio.
The mission is to focus on identifying, quantifying, and communicating the medical value proposition of molecules in the oncology portfolio. O2R is a thought partner for the Franchise Leads and an important member of the Global and US Core Medical Team. Activities focus on the generation
of evidence to assist payer and health care provider (HCP) decision-makers and include scientific evidence for reimbursement dossiers and market access.
The deliverables from this team have a significant impact on the success of the global medical strategy. The Senior Scientist is an individual contributor role and will be a crucial member of an Asset team that is collectively responsible for delivering strategic plans and implementing projects. The Senior Scientist reports to the Asset Lead, Oncology Outcomes Research , and will be responsible for leading the execution of health outcomes and real-world strategies and studies on a global and US market level. This role is also responsible
for working with key internal collaborators supporting the execution and communication of studies.
This position requires an individual with scientific knowledge of HEOR and its application throughout development process, business insight, and interpersonal skills. What You'll Do: Responsible for the execution of the Asset strategy for the Oncology Outcomes Research team, and other activities to backss, quantify and communicate the value proposition for the asset. Responsible for specific Global and US Regional health outcomes strategy. Conduct outstanding quality research that is medically relevant, scientifically valid, and aligned with the evidence generation and communication needs.
Will support asset leads and work with outcomes researchers with diverse technical skills. Present research findings at scientific congresses and participate in the development and writing of manuscripts for publication in peer-reviewed journals. Translate output from research into tools and resources for field teams. Manage relationships and budgets with vendors to ensure timely completion of high quality, projects. Maintain in-depth knowledge of the disease state, market & customer dynamics, the competitive landscape, and reimbursement issues Minimum Qualifications: Minimum of 1 year experience, preferably in the medical industry, graduate degree strongly preferred (Ph D, MS, MPH) in health economics, epidemiology, outcomes research and/or related fields.
Understanding and knowledge and application of epidemiological/health outcomes methodology within medical industry at an international level. In-depth expertise with research methods for real world research, HEOR projects including pharmacoepidemiologic models. Demonstrates analytical, judgment and problem-solving skills. Travel-10% Preferred Qualifications: Advanced Scientific degree3 years of HEOR or Outcomes Research experience within industry Standout colleague and supports the asset team within the O2R organization.
Strong written and verbal communication skills as well as interpersonal skills. Next Steps - Apply today! Are you ready to bring new insights and fresh thinking to the table? Brilliant! We have one seat available, and we hope it's yours. Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.
We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. Date Posted 21-Dec-2023 Closing Date Our mission is to build an inclusive and equitable environment. We want people to feel they belong at Astra Zeneca and Alexion, starting with our recruitment process.
We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
One year prior clinical experience as a licensed Physical Therapist is required. As a home care Physical Therapist, you will be an integral member of a multi-disciplinary health care team that provides rehabilitative care and skilled nursing to clients, affording them the opportunity to receive the medical care required to remain at home.
FULL TIME BENEFITS WEEKLY PAY NO WEEKENDS or NIGHTS MILEAGE REIMBURSMENT CLICK HERE to schedule a quick call and learn more! At BAYADA, we believe our employees are our greatest asset. We are committed to investing in people and nurturing their desire to grow. Watch this video to learn more about field employee career pathing: Sign on bonus for Full
Time. Responsibilities for a PT - Physical Therapist include: Make home visits to clients in designated geographic territories. Perform diagnostic tests and measurements, such as the mobility/range of joints, transfer status, stability, patterns and appearance of ambulation, strength and endurance of muscles, balance testing, and safety backssments.
Develop and implement appropriate individualized care plans, including manual therapeutic exercises, gait training, balance, and other interventions. Continually backss and revise the Physical Therapy - PT care plan, and participate with nursing in the multidisciplinary care plan, as appropriate. Educate and instruct clients, family members,
or other client representatives, in rehabilitative care and activities necessary to promote the client's health, safety, and independent living.
Accurately document observations, interventions, and evaluations pertaining to client care management and services provided, utilizing a state-of-the-art touch pad tablet. Qualifications for a PT - Physical Therapist include: A current VERMONT Physical Therapist - PT license. A minimum of one year of recent work experience as a Physical Therapist - PT. Graduation from a program approved by the American Physical Therapy Association or the Committee on Allied Health Education and Accreditation of the American Medical Association, as indicated by school transcript or diploma.
Ability to work independently and manage time effectively. Strong interpersonal, organizational, and problem solving skills. Solid computer skills; prior experience with electronic medical records (EMR) preferred. BAYADA believes that our employees are our greatest asset: BAYADA offers a comprehensive benefits plan that includes the following: Paid holidays, vacation and sick leave, vision, dental and medical health plans, employer paid life insurance, 401k with company match, direct deposit and employee assistance program To learn more about BAYADA Benefits, click here Enjoy being part of a team that cares and a company that believes in leading with our values.
Feel confident, safe, and supported with PPE supplies, comprehensive infection prevention protocol, daily pre-screens, and close monitoring of the COVID-19 outbreak. Develop your skills with training and scholarship opportunities. Advance your career with specially designed career tracks. Be recognized and rewarded for your compassion, excellence, and reliability. Benefits may include medical, dental, and life insurance; mileage reimbursement; paid time off; weekly pay and direct deposit; scholarship opportunities; one-on-one training; recognition programs; referral bonuses; 401(k) with company match; and opportunities for career advancement.
As an accredited, regulated, certified, and licensed home health care provider, BAYADA complies with all state/local mandates. BAYADA Home Health Care, Inc. and its associated entities and joint venture partners, are Equal Opportunity Employers. All employment decisions are made on a non-discriminatory basis without regard to interaction, race, color, age, disability, pregnancy or maternity, interactionual orientation, gender identity, citizenship status, military status, or any other similarly protected status in accordance with federal, state and local laws.
Hence, we strongly encourage applications from people with these identities or who are members of other marginalized communities. For more details: jobs-search. org/physical-therapist_bennington-c449179/physical-therapist-home-health-bennington_i1969780615
be the one for you! About Astra Zeneca At Astra Zeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing.
We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people's exceptional skills with those of people from all over the globe. As a part of our Biologics Engineering team in Gaithersburg, MD, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives. About Astra Zeneca in Gaithersburg, MD Our Gaithersburg,
Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC.
This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes
a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center.
This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. Summary of the Group The Biologics Engineering department at Astra Zeneca is constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're utilizing our expertise in protein and antibody engineering to enable novel therapeutic approaches to Oncology, Respiratory, Inflammatory, Cardiovascular and Infectious disease.
We offer a unique and strong collaborative network as part of the Astra Zeneca family, as together we explore new and exciting technologies. The Biologics Engineering group is seeking a creative and talented Senior Scientist to join out Hybridoma team. The successful candidate will have strong background in Immunology/ Cell biology and will be conducting hybridoma campaigns to identify novel antibodies to different therapeutic targets. The applicant will operate independently and in collaboration with other team members and scientists across research to develop our next generation of drugs.
What you will do: As a Senior Scientist within the Hybridoma group, you will design and execute projects from target validation to therapeutic antibody discovery using the hybridoma/B-cell platform Dial in new technologies or improve existing methods to ensure consistent innovation in drug discovery Collaborate and work with different therapeutic teams to drive pipeline progression Interpret data, provide analysis and present data within and across teams Education & Experience Requirements : Ph D degree in Immunology/ Cell Biology or other related field with 0- 2 years postdoctoral or industry experience (preferred)OR Master's degree with 6+ years of relevant experience in industry (preferred) or academia Required Skills : Must have hands-on experience in hybridoma technology, including but not limited to designing experiments, immunogen preparation, animal immunization, cell culture, cell fusion and post-fusion screening.
Experience performing high-throughput screening methods( ELISA, Flow cytometry)Demonstrated experience in optimizing/troubleshooting protocols with a problem-solving mindset. Ability to learn and embrace new technologies quickly, work independently, multi-task and manage shifting priorities Rigorous logical thinking, good communication skills and the ability to work within teams.
Maintain up-to-date knowledge of the latest advances in antibody discovery technologies, and contribute to the development of new and innovative approaches. Excellent organizational skills and data presentation. Desired Skills : Experience with NGS and 10XGenomics for antibody discovery using hybridoma/ B-cell technologies Familiarity with automation and high-throughput screening platforms (e. g. Hamilton, i Que3) Experience with fluorescence activated cell sorting (FACS) for single B cell cloning.
" When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. " Date Posted 05-Dec-2023 Closing Date 30-Dec-2023Astra Zeneca embraces diversity and equality of opportunity.
We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e. g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.
Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
execution, and interpretation of mid/high throughput cellular assays and mechanistic experimentation to advance early drug discovery projects. The candidate will work closely with a team of multidisciplinary quantitative scientists and other stakeholders to enable strategies for screening, assays/models, and key studies to advance a diverse portfolio of small molecule and biologic preclinical candidates targeting cardiometabolic diseases, immunology, and oncology.
We value transparent communication, creative-thinking, teamwork, and rigorous scientific exploration. If you are a highly motivated individual and team player with a strong desire to impact drug discovery across multiple therapeutic
areas, we invite you to consider joining our team. Key job duties: Provide cellular pharmacology and assay development expertise to support early drug discovery across multiple therapeutic areas (cardiometabolic, immunology, and oncology) Develop and execute cellular assays for compound screen and mechanistic characterization of diverse targets and pathways, using a wide range of experimental methodology Implement best experimental practices and leverage lab automation to improve assay operation, quality, and overall productivity Identify, evaluate, and champion new enabling technologies and methods Ensure high-quality data analysis and timely report generation to project teams Properly document
experimental designs, findings, and assay protocols, and comply with all laboratory training and safety requirements Collaborate with colleagues on multi-disciplinary project teams to provide scientific/technical contributions and deliver on project goals Education: Bachelor's in Pharmacology, Cell Biology or a relevant scientific discipline with ten (10) years of drug discovery experience in a biotech/medical setting Master's in Pharmacology, Cell Biology or a relevant scientific discipline with seven (7) years of drug discovery experience in a biotech/medical setting Required Experience and Skills: Highly skilled in the development, execution, and interpretation of mid/high throughput cell assays, as well as extensive experience with compound screening and lead discovery support Demonstrated proficiency in a wide range of cell biology techniques (mammalian cell culture, transfection/transduction, CRISPR, etc.
) and relevant assay detection technologies (ELISA, Alpha LISA, TR-FRET/BRET, etc. ) Broad knowledge and hands-on experience with automated liquid handling instruments (Biomek, Bravo, Echo, etc. ) and integrated robotic systems for assay operation Experience with automated data processing, curve fitting, and visualization software tools Rigorous quantitative experimentalist with excellent organization and communication skills and a strong growth mindset Demonstrated ability to multi-task and work collaboratively in a cross-functional team environment to execute on project goals and advance drug discovery Preferred Experience and Skills: Hands-on experience with high-content imaging methods and automated image analysis Hand-on experience with the development and execution of radioligand binding assays Familiarity with the development and execution of more complex cellular models, such as those with primary cells or i PSCs, co-culture systems, 3D spheroids & organoids Prior experience with multiple therapeutic modalities (small molecule, peptide, antibody, antibody drug conjugate, etc.
) #Eligiblefor ERP Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).
Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, interaction, interactionual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics.
For more information about personal rights under the U. S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement Pay Transparency Nondiscrimination We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment.
We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts U. S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U. S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.
This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as " remote"Under New York State, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job.
Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education. Expected salary range: $120,800.00 - $190,200.00Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days.
For Washington State Jobs, a summary of benefits is listed here. Search Firm Representatives Please Read Carefully Merck & Co. Inc. Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place.
Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: No Travel Requirements: No Travel Required Flexible Work Arrangements: On-Site Shift: 1st - Day Valid Driving License: No Hazardous Material(s): Yes Requisition ID: R273454PDN-9ae7de5a-ecee-433d-a73c-57ff70ac21e5
and professionally through various resources and programs. New York Life is a relationship-based company and appreciates how both virtual and in-person interactions support our culture. Job Title: NYL Internship: Data Scientist New York Life's AI and Data team , led by Chief Data and Analytics Officer Don Vu delivers innovative data, insights and AI solutions for the organization.
Our AI team works on a diverse portfolio of AI and Gen AI projects, by combining agile and entrepreneurial drive with industry-leading methods and tools. Our efforts are fully supported by executive leadership, and we work hand in hand with our Business Partners through all stages of model development from ideation
to deployment. As it takes multiple skill sets to deliver AI models to production, our AI team includes product managers, data scientists, MLOps engineers, program managers, a model validation & governance group, and a communications & development group.
The AI team is looking to hire summer interns who are graduate students or recent graduates. The internships start in May / June with full time hours (40 hours per week). Ideal candidates have or are in the process of obtaining a Master's or Ph D in Statistics, Data Science, Computer Science with Data Science emphasis or another field which is highly analytical and quantitative. As a member of our team, you will have the opportunity to
gain real-life work experience, develop your skills, and begin building a network in a professional environment.
Qualifications Recipient or in process of obtaining a Master's or Ph D in Statistics, Data Science, Computer Science, Applied Mathematics or another field which is highly analytical / quantitative in nature Experience with standard machine learning / statistical techniques: GLM, Logistic Regression, GBM, Random Forests, Experimental Design, etc. Exposure to deep learning methods Excellent skills in Python or R Good feature engineering skills, ability to use SQL if needed Strong business sense Self-directed and independent Compensation is competitive.
Relocation / housing support will not be provided. The position is located in Manhattan (Madison and 27th, walking distance from Penn Station and Grand Central Station) on a hybrid schedule for 10 - 12 weeks. Recognized as one of Fortune's World's Most Admired Companies, New York Life is committed to improving local communities through a culture of employee giving and volunteerism, supported by the Foundation. We're proud that due to our mutuality, we operate in the best interests of our policy owners. We invite you to bring your talents to New York Life, so we can continue to help families and businesses " Be Good At Life.
" To learn more, please visit Linked In , our Newsroom and the Careers page of . Salary range: $40 per hour Overtime eligible: Exempt Discretionary bonus eligible: No Sales bonus eligible: No Click here to learn more about our benefits. Starting salary is dependent upon several factors including previous work experience, specific industry experience, and/or skills required. Recognized as one of Fortune's World's Most Admired Companies, New York Life is committed to improving local communities through a culture of employee giving and volunteerism, supported by the Foundation.
We're proud that due to our mutuality, we operate in the best interests of our policy owners. We invite you to bring your talents to New York Life, so we can continue to help families and businesses " Be Good At Life. " To learn more, please visit Linked In , our Newsroom and the Careers page of . Job Requisition ID:89478PDN-9a22deef-36d8-46e9-911a-b8cb330c10a1
He/She will be a key player in providing high quality, well-characterized proteins to support biologics discovery across multiple therapeutic indications. The successful candidate will be a well-organized and a highly productive scientist that can design and execute experiments efficiently, analyze, interpret, and present data to multidisciplinary project teams.
Astra Zeneca is an exciting company with long-standing tradition of excellence in drug discovery that offers a fantastic culture and great opportunities to enhance your skills and grow your career. At Astra Zeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking
big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.
Responsibilities Perform expression and purification of mono- and multi-specific antibodies and complex modalities fusion proteins from sub-milligram to gram scale to support antibody discovery, characterization, and pre-clinical validation of leads. Perform biologics quality backssment utilizing a variety of techniques, such as CE-SDS, SEC-HPLC, endotoxin assay, etc. Develop and implement purification procedures to improve existing processes and workflows in coordination with BPD. Maintain
and troubleshoot laboratory instrumentation, such as AKTA-Pure, AKTA-Avant, Am Mag, Lab Chip, etc.
Collaborate and work with a diverse group of scientists across all therapeutic areas to ensure timely progress of research projects. Represent BET function on cross-functional teams, providing technical expertise, progress updates and data summaries. Maintain complete and updated records in electronic lab notebook. Required Skills B. S, with 8+, M. S. with 5+ or Ph. D. with 2+ years of experience in Biologics production at Biotech/ Big Pharma Extensive hands-on experience with transient mammalian expression (HEK293 and CHO) and purification of mono- and bi-specific antibodies, Fab fragments, sc Fv, VHH, and various antibody-fusion formats.
Demonstrated proficiency with various modes of chromatography, including affinity, IEX, mixed mode, HIC, and SEC. Deep and current knowledge of resigns, membranes and suppliers. Extensive hands-on experience with chromatography instrumentation (AKTA-Pure, AKTA-Avant, Am Mag) including ability to develop custom methods and troubleshoot. Experience with automation is preferred. Strong protein characterization and QC skills including analytical SEC, CE-SDS, endotoxin assays, etc. Familiarity with molecular biology techniques, including primer design, gene assembly, Gibson and Golden gate cloning, vector assembly, transfection, and software for sequence analysis.
Experience interacting with CMC groups and understanding development upstream and downstream processes, including ultrafiltration, viral clearance, etc. is highly desired. Proven ability to work independently, effectively plan and organize work activities, and prioritize task completion to meet project deadlines in a fast-paced industrial environment. Strong interpersonal and communication skills, ability to collaborate and communicate across disciplines.
About Astra Zeneca in Gaithersburg, MD: Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees stay happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly designed, activity-based workspaces to suit a variety of working styles while increasing collaboration between teams. " When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform to connect, work at pace and challenge perceptions.
That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. " Date Posted 21-Nov-2023 Closing Date 30-Dec-2023Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.
We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e. g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
Astra Zeneca in Gaithersburg, MD Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US.
Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. The Gaithersburg site offers a variety of amenities to help boost productivity and
help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center.
This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. Summary of the Group Biologics Engineering is responsible for the discovery, design, engineering, and optimization of next generation biologics to create biological drug candidates against diseases with improved safety and efficacy. The Multi-specific Engineering Team designs, engineers, and optimizes complex therapeutics through structure-function
principles while collaborating broadly across the AZ Research organization.
We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for the development of in-house biologics discovery platforms and novel drug modalities to address unmet medical needs. Main Duties & Responsibilities Seeking a skilled and highly motivated scientist to enhance our antibody-based platform technology efforts. The successful candidate will be excited by research at the interface where innovative technology meets Biology. Lead collaborative workstreams with a diverse group of scientists across all therapeutic areas to ensure timely progress in research projects and drive technological innovations.
Conceive, design, and execute the engineering of innovative multispecific antibodies with improved selectivity and developability Biochemical, biophysical and functional characterization of antibodies and multispecific modalities Prepare, analyze, and present data internally and externally Education & Experience Requirements Fresh Ph D in Biotechnology, Molecular Biology, Biochemistry or other relevant scientific field. Required Skills Extensive hands-on experience in molecular biology and antibody engineering, including; design, expression, purification and biochemical/biophysical characterization of various bispecific antibody formats Proven ability to work independently, effectively plan and organize work activities and prioritize task completion to meet project deadlines Deep understanding of various imaging/multicolor flow cytometry-based instruments and data analysis programs Comprehensive experience in tissue culture techniques and functional cell-based assay development Demonstrated experience in optimizing/troubleshooting protocols with a problem-solving mindset Track record of scientific innovation as evidenced by scientific publications, patents and oral presentations at conferences Desired Skills and experience: 2+ years of post-doctoral experience in antibody engineering and/or bispecific antibody technologies.
Understanding of protein structure-function relationships and antibody structural remodeling Experience in engineering antibodies with improved properties (e. g. affinity, solubility, and other attributes related to developability)Background in antibody discovery using one of several display-based technologies Working knowledge of automation and high-throughput screening from bacterial or mammalian expression systeminteractionperience in immunocytokine and T-cell engager Excellent written and verbal communication skills and effective presentation of complex scientific data to cross-functional and senior management Date Posted 09-Nov-2023 Closing Date 30-Dec-2023Astra Zeneca embraces diversity and equality of opportunity.
We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be.
We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e. g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
