Senior Scientist

patients with inherited glaucoma and other inherited optic nerve diseases. This position assists the Principal Investigator (Dr. John Fingert, MD, Ph D) in the design, interpretation, and control of experiments in a cellular and molecular research laboratory.

The Assistant Research Scientist/Engineer also coordinates and supervises task execution by technicians and students, including the interpretation and evaluation of research data. Key duties include: Assist in designing and planning experiments for various projects with the Principal Investigator, including in-depth literature research to evaluate the current standard for specific experimental protocols. May coordinate responsibilities

for ongoing research among technicians and students, as well as interpret and evaluate results in real time. Generate, maintain, and differentiate human induced pluripotent stem cells for use in disease modeling projects.

Use recombinant DNA techniques to correct mutations in patient-derived cells and analyze correction efficiency. Tasks may include identifying the genomic target, building the targeting and correction cassettes, testing the efficiency of targeting and correction in HEK cells and patient cell lines, and analyzing results to determine off-targeting effects. Assist the Principal Investigator in compilation and evaluation of data for preparation of manuscripts for publication

in scientific journals, grant applications, and posters/talks for local and international scientific conferences.

Prepare posters/talks and represent the Dr. John Fingert lab at local and international scientific conferences as needed. Contribute to new or continuing research grant proposals to obtain funding for research activities as well as to progress reports required by funding agencies. Supervise adherence to safety and compliance guidelines when necessary. University of Iowa Hospitals & Clinics-recognized as one of the best hospitals in the United States-is Iowa's only comprehensive academic medical center and a regional referral center.

Each day more than 12,000 employees, students, and volunteers work together to provide safe, quality health care and excellent service for our patients. Simply stated, our mission is: Changing Medicine. Changing Lives. ®Percent of Time: 100%Schedule: Monday - Friday, 8:00a-5:00p Location: UIHC, Iowa City Rotations: N/AWork Modality: This position is performed fully on campus. Salary: $53,192 - Commensurate Pay Level: 5AREQUIRED QUALIFICATIONS A Ph. D. in Biology, Molecular Biology, or another related biological science field, and one or more years of postdoctoral training with progressively responsible work experience.

Demonstrated experience in human i PSC generation, maintenance, and differentiation, and aseptic technique Experience with standard molecular biology and biochemical techniques (e. g. cloning, nucleic acid and protein isolation from human and animal tissue samples, PCR/q PCR, and Western blot), common cell biology techniques (e. g. immunocytochemistry/immunohistochemistry), and tissue culture techniques (i. e. establishing and maintaining primary cell lines and human i PSCs). Excellent oral and written communication skills DESIRED QUALIFICATIONS Three or more years of experience in cellular and molecular biology research of human disease Experience with CRISPR-Cas genome editing technology Strong publication record Proficiency with Macintosh computers, including the applications Microsoft Word, Excel, Powerpoint, Adobe Photoshop, Laser Gene, and End Note software Previous experience supervising students and technicians in a research laboratory setting.

POSITION & APPLICATION DETAILSIn order to be considered for an interview, applicants must upload the following documents and mark them as a " Relevant File" to the submission: Resume Cover Letter Job openings are posted for a minimum of 14 calendar days and may be removed from posting and filled any time after the original posting period has ended.

Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check and credential/education verification. Up to 5 professional references will be requested at a later step in the recruitment process. This position is not eligible for University sponsorship for employment authorization. For additional questions, please contact Melissa Monhollon, HR Manager, at or 319-356-xyz X.

Additional Information Classification Title: Asst Research Scientist/Engin Appointment Type: Professional and Scientific Schedule: Full-time Work Modality Options: On Campus Compensation Pay Level: 5A Contact Information Organization: Healthcare Contact Name: Melissa Monhollon Contact Email: University of Iowa is an equal opportunity/affirmative action employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, religion, national origin, age, interaction, pregnancy (including childbirth and related conditions), disability, genetic information, status as a U.

S. veteran, service in the U. S. military, interactionual orientation, gender identity, or associational preferences.

of receipt and require identification and quantification. This position will be responsible for receipt of specimens, specimen preparation, specimen analysis, data processing and reporting of results from 20 or more specimens received on a weekly basis. The Scientist will be responsible for operating and maintaining instruments, including a high-resolution mass spectrometer and LC-MS/MS, and associated equipment to ensure prompt analytical response and minimal turnaround times back to facilities.

Additional duties include method development and outreach/training to first responder organizations. Schedule: Normal working hours are 8am to 5pm, Monday through Friday. However, this position

must be willing to be available to respond to emergency response analyses at potentially unconventional business hours or on the weekend in emergency situations.

Modality: In-Person, on-site. For a full job description, please send an e-mail to the contact listed below. About the State Hygienic Laboratory The State Hygienic Laboratory's main facilities are headquartered on the University of Iowa's Research Park campus northwest of Iowa City in Coralville. Additional testing facilities are part of the Iowa Laboratory Facilities in Ankeny, a Des Moines suburb. Since 1904, the State Hygienic Laboratory has been at the forefront of public health issues in Iowa. As the state's public health

and environmental laboratory, the Hygienic Laboratory serves all of Iowa's 99 counties through disease detection, environmental monitoring, and newborn and maternal screening.

Qualifications: Education or Equivalency Required A Master's degree in chemistry or analytical toxicology, including extensive knowledge of analytical instrumentation and method development/validation, or an equivalent combination of education and experience is required. Required Qualifications Considerable experience (typically 3 years) in appropriate laboratory techniques is required. Considerable experience with specific instrumentation including High Resolution Mass Spectrometers, LC-MS/MS, and GC-MS.

Excellent written and verbal communication skills. Demonstrate a commitment to diversity, equity, and inclusion. This will include the ability to work with a variety of individuals and groups in a constructive and respectful manner, while appreciating the unique contribution that an inclusive workforce will foster. Possession of a valid state or commercial driver's license, and the ability to meet University Fleet Safety Standards. Highly Desirable Qualifications Ph D in chemistry or analytical toxicology with extensive knowledge of analytical instrumentation and method development/validation.

Desirable Qualifications Reasonable experience in laboratory supervision is desirable. Previous training and work with potentially infectious materials and hazardous materials is desirable. Position and Application Details and Instructions: Include your driver's license information as a certification under the license and certifications section. In order to be considered for an interview, applicants must upload the following required documents and mark them as a " Relevant File" to the submission: Cover Letter Resume Job openings are posted for a minimum of 14 calendar days and may be removed from posting and filled any time after the original posting period has ended.

Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check, credential/education verification and verification of a valid state or commercial driver's license, and ability to meet University Fleet Safety Standards. Up to 5 professional references will be requested at a later step in the recruitment process. For additional questions, please contact: VPR Talent ()Additional Information Classification Title: Environmental Lab Scientist Appointment Type: Professional and Scientific Schedule: Full-time Work Modality Options: On Campus Compensation Pay Level: 6A Contact Information Organization: Research/Hygienics Lab Contact Name: VPR Talent Contact Email: University of Iowa is an equal opportunity/affirmative action employer.

All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, religion, national origin, age, interaction, pregnancy (including childbirth and related conditions), disability, genetic information, status as a U.

S. veteran, service in the U. S. military, interactionual orientation, gender identity, or associational preferences.