m RNA – Sr. Scientist

Detailed Information

LISTED SITE
  • Location: Waltham, MA

  • Company: Sanofi US

Science in Waltham, MA

POPULAR
Formulation Chemist
1
Formulation Chemist
Waltham, MA
Jul 08, 2023

they do. Role & Responsibilities As the R&D Chemist you will assist in formulating new products as requested by Marketing, assist in re-formulating current product lines for improvement, and assist in solving technical scale-up and manufacturing problems by ensuring the availability of quality and value engineered products which satisfy customer's requirements and increase sales and profitability of the corporation.

Formulation of existing and new projects for the general industrial coatings business line. This will be the lead chemist and own all product development, quality, and manufacturing aspects as it relates to the formulas. Test and evaluate products. Write SDS and keep low or

no VOC Compliance. Update and improve existing products, materials and test methods. Provide technical support to Production, Sales, and Marketing in support of product scale-up, quality control, application testing, and other cross-functional activities.

Digitally maintain detailed technical records of lab work. Critical thinking skills Self-Motivated and Task Oriented. Knows how to monitor workload. Ability to multi-task and wear many hats daily, enjoy a variety in the work. Strong Interpersonal Skills Someone who enjoys a small company culture and works well with others. (75 people in company) Proficient Microsoft Office & Outlook Strong Organizational Skills & Project Management Skills

Creative thinker that may see new application uses, market potential.

Qualifications And Education Requirements BS in Chemistry or Related Field2-3 years of developing formulations from inception through scale up and commercialization Strong understanding of industrial formulations specific to coatings, adhesives and sealants#LI-SL3At Shark Ninja, Diversity, Equity, and Inclusion are vital to our global success. Valuing each unique voice and blending all of our diverse skills strengthens Shark Ninja's innovation every day. We support ALL associates in bringing their authentic selves to work, making an impact, and having the opportunity for career acceleration.

With help from our leadership, associates, and our community, we aim to have equity be a key component of the Shark Ninja DNA. YOUR ROLE in leading our SUCCESS DRIVERS & representing our UNIQUE MINDSET Lead us to be " RARELY SATISFIED" Make things better each day; " PROGRESS OVER PERFECTION" Use your knowledge of our consumer, understand that " DETAILS MAKE THE DIFFERENCE" Deliver something great; " WINNING IS A TEAM SPORT" Be clear and honest, " COMMUNICATING FOR IMPACT" Explore Shark Ninja on our social channels: Instagram Linked In Shark Ninja's Candidate Privacy Notice can be found here: /candidate-privacy-notice/ We do not discriminate on the basis of race, religion, color, national origin, interaction, gender, gender expression, interactionual orientation, age, marital status, veteran status, disability, or any other class protected by legislation, and local law.

Shark Ninja will consider reasonable accommodations consistent with legislation, and local law. If you require a reasonable accommodation to participate in the job application or interview process, please contact Shark Ninja People & Culture at xyz X@ PDN-9995f10b-e87f-47c2-81d7-b03ee2a03c81

POPULAR
Lead Environmental Scientist
1
Lead Environmental Scientist
Waltham, MA
Dec 21, 2023

a Environmental Scientist - Environmental Licensing-Permitting and Compliance for Operations Support, Environmental, New England department based in Waltham, MA This is a Hybrid Role - Must live within a commutable distance to Waltham, MA Job Purpose Ensure facility compliance with applicable regulatory requirements, facilitate licensing & permitting of projects, and advance the overall environmental policy of National Grid primarily at its liquefied natural gas (LNG) facilities, but for gas transmission and complex distribution projects as needed.

Key Accountabilities Performing activities to ensure regulatory compliance at National Grid's LNG facilities including but not limited to:

Conducting routine compliance inspections. Conducting air emission permitting, monitoring, and reporting at regular frequencies. Ensuring each facility's annual air emission log is maintained and accurate.

Coordinate stack testing, where applicable. Coordinating the overall environmental licensing & permitting process to obtain environmental permits in a timely manner to meet operations and construction schedules for major and minor facility upgrades, improvements, repairs at National Grid's LNG facilities. On an as needed basis, coordinate environmental licensing and permitting activities to obtain environmental permits for gas transmission and complex distribution projects. Providing

daily/weekly construction coordination and oversight of complex facility upgrade projects.

Serving as the environmental subject matter expert (SME) for any and all LNG matters, and establishing a true partnership with LNG Operations to ensure high environmental performance. Developing and implementing innovative environmental permitting strategies that maximize the opportunity for regulatory compliance while minimizing operating and capital costs. Providing technical and regulatory guidance, support and coaching to share knowledge and develop understanding of environmental requirements. Managing consultants and contractors in securing necessary permits and approvals as well as during project monitoring to support construction activities.

Anticipating, tracking, influencing, and backssing the impact of emerging environmental regulations so as to minimize the economic and operational impact on National Grid. Monitoring and analyzing data to track environmental performance, and where necessary, conducting investigations to develop corrective actions for performance improvement. Managing processes and programs to develop and submit all required compliance reports to applicable regulatory agencies. Communicating and defending the company's environmental reputation at hearings, public meetings, with the media and with other key stakeholders.

Promoting the National Grid brand to be the foremost energy company and to safeguard the environment for future generations. Performing other environmental-related activities for any National Grid operating company as requested. Qualifications Knowledge & Experience Required: Comprehensive knowledge of federal, state, and local environmental licensing & permitting regulations to facilitate LNG maintenance, upgrade or improvement projects in Massachusetts and Rhode Island. Minimum 7+ years of experience conducting and/or overseeing environmental licensing & permitting and compliance activities in New England, preferably related to utility operations.

Strong track record of developing innovative environmental permitting and compliance strategies which achieve environmental protection objectives cost effectively while retaining operational flexibility. Demonstrated record of professional respect and credibility among federal, state and local environmental regulatory, legislative, citizen group, media and other stakeholders. Exhibit high personal standards of commitment and integrity. Job Qualifications: 10+ years experience in environmental licensing and permitting activities or equivalent experience A Bachelor's degree in engineering, applied sciences, or environmental management.

Graduate level education a plus. More Information #LI-JF1#LI-HYBRID Salary $117,000 - $139,000 a year Salary commensurate with location and experience This position has a career path which provides for advancement opportunities within and across bands as you develop and evolve in the position; gaining experience, expertise and acquiring and applying technical skills. Candidates will be backssed and provided offers against the minimum qualifications of this role and their individual experience.

National Grid is an equal opportunity employer that values a broad diversity of talent, knowledge, experience and expertise. We foster a culture of inclusion that drives employee engagement to deliver superior performance to the communities we serve. National Grid is proud to be an affirmative action employer. We encourage minorities, women, individuals with disabilities and protected veterans to join the National Grid team. PDN-9ae5e3bd-b9ed-4991-8de2-49a6e828c6ec

POPULAR
Lead Computational Chemist - Oncology R&D
1
Lead Computational Chemist - Oncology R&D
Waltham, MA
Dec 22, 2023

Astra Zeneca is a global, science-led, patient-focused biomedical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading medical companies.

At AZ, we're proud to have an exceptional workplace culture that encourages innovation and collaboration. Here, employees are empowered to express different perspectives - and made to feel valued, energized and rewarded for their ideas and creativity. AZ is a place where passionate people can immerse themselves in their work and make significant contributions to scientific excellence and medicines - does this describe

a place where you would like to work? At Astra Zeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.

We're passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life! Astra Zeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer and to ultimately eliminate cancer as a cause of death! What you'll do: We are seeking a computational

chemist for our Oncology medicinal chemistry department based in Waltham, Massachusetts.

The successful candidate will be a professional computational chemist, with a passion for drug discovery and ideally experience of working in drug discovery project teams within a biotech or medical setting. You will be working closely with an established, transnational team of computational chemists within Astra Zeneca working on oncology drug discovery projects across a range of modalities and will have access to innovative computational methods, such as our FEP and AI platforms, and excellent lead generation capabilities. Major Responsibilities: As a leading member of the medicinal chemistry design team, you will be responsible for: Setting and delivering on computational and medicinal chemistry strategies to impact project success at all stages from drug target identification through to clinical candidate nomination.

You will have accountability for setting the computational chemistry strategy, carrying out structure- and ligand-based design and data analysis, extracting insight from large proprietary structural biology and SAR data sets; your contributions to molecular design will be expected to result in inventorship on patent applications. You will work closely with scientists from other disciplines including structural biology, biophysics, ADME/DMPK and safety sciences as part of the wider drug discovery project team and will present your work regularly to peers and senior partners.

Depending on experience and interest, you might also function as the lead chemist for a drug discovery project. At Astra Zeneca, we value scientific innovation. Maintaining an awareness of the current state-of-the art, you will identify promising new computational methodologies or technologies that could benefit drug discovery and will develop and implement these through internal or external collaborations, sharing exemplary practice across Astra Zeneca.

You will be expected to publish your work regularly in high quality scientific journals and at national and international conferences. You'll have the opportunity to build academic collaborations and to supervise graduate scientists and postdocs, as well as to mentor colleagues. The scope for personal development is vast. Education, Qualifications, Skills and Experience: Requirements: Ph. D. degree in computational chemistry (or similar), ideally with greater than 5 years of experience working as a computational chemist on drug discovery projects in a medical or Biotech setting, or B.

Sc. /M. Sc with 10+ years of experience Broad experience in protein structure and dynamics, structure- and ligand-based design, data analysis and/or property prediction A passion for drug discovery and an excellent understanding of medicinal chemistry concepts Innovative problem-solver, with a track record of impacting drug project delivery Scientific and project impact exemplified by high quality scientific publications Strong oral and written communication skills, team-working and time-management skills Why Astra Zeneca?

At Astra Zeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-medical company can be. This means we're opening new ways to work, pioneering innovative methods and bringing unexpected teams together. Interested? Come and join our journey. Site Description: Our Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park Bio Hub, just west of the city center.

Our Bio Hub facility, is a bold new R&D initiative, which cultivates life science discoveries and the exchange of ideas. Here, we play host to some of the most ground breaking technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to crafting a culture of inclusion and collaboration.

With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers. Our Waltham site offers a variety of amenities to help book efficiency and help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, & full-service cafeteria. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while growing collaboration between teams and the greater research community. So, what's next?

A place built on courage, curiosity, and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take calculated risks that write the next chapter for our pipeline. If you are swift to action, confident to lead, willing to collaborate, and passionate about the possibilities, then we are keen to hear from you! Where can I find out more? Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Next steps : Apply today, or connect with our Talent Acquisition Partner - Kayla Harris: /in/kayla-harris-8723ab13b/ for a confidential discussion to explore this opportunity further.

We are looking forward to hearing from you! Date Posted 13-Nov-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e.

g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

POPULAR
Senior Scientist Translational PKPD
1
Senior Scientist Translational PKPD
Waltham, MA
Dec 22, 2023

We currently have an exciting opportunity for someone who has a passion for PKPD modeling and DMPK science, applied to Cancer biology, ideally with experience of working with large molecule drug projects to join our team. As a Senior Scientist Translational PKPD, you will have the opportunity to drive strategy and provide global leadership in PKPD science on Antibody drug conjugates and Radio immuno- conjugates.

Your day-to-day role is to provide projects with specialist modeling input into exploring the PK/PD/Efficacy in pre-clinical models, and using these models in order to iteratively build an understanding of the dose & schedule requirements for therapeutic intervention across different

patient populations as a single agent and combined with other agents. Accountabilities: Representing Translational PKPD group and providing overall scientific leadership for cross functional and external collaborations involving DMPK.

Exploring the effects on target and pathway to understand the requirements for efficacy and set a candidate drug target profile (CDTP). Predicting human dose and regimen together with providing input into exposure and pharmacodynamic (PD) biomarker based decision criteria for early clinical trials. Driving learning through back translation of early clinical exposure and PD data and providing prioritized future options for clinical testing. Leading and participating

in Oncology strategic scientific initiatives and continuous improvement projects by providing expert M&S knowledge.

Having a breadth of influence and impact across Astra Zeneca Clinical Pharmacology and externally within their discipline. Identifying, championing and developing new insights. Leading scientific discipline networks and acting as a focus for debate within the Astra Zeneca scientific community. Advising on and participating in the development of Discovery or Development strategies in PKPD. Managing student and Post Doc programmes. Leading external collaborative projects with academic or cross-pharma pre-competitive groups. Providing disciplinary scientific leadership and presenting work through patents, publications and lectures.

Requirements: Education: Ph D, Completing Ph D before start date of position (preferably February 2024), Masters with at least 3 years of experience, or equivalent degree in a field with a significant component of Modeling & Simulation, such as systems biology, quantitative pharmacology, pharmacometrics, chemical engineering, physics, medical sciences or applied mathematics. 0-4 years of experience in a subject area with a significant component of Modeling & Simulation, such as systems biology, quantitative pharmacology, pharmacometrics, chemical engineering, physics, medical sciences or applied mathematics.

Desirable Experience: Relevant industry experience in Modeling & Simulation, ideally in preclinical/translational setting with a focus on ADC or RIC, or a MS degree with proven industry experience. Experience in a project-facing role within medical R&D. Comprehensive understanding of DMPK and pharmacology/safety aspects of drug discovery and development with a strong publication record. Track record of supporting PK, PKPD and TKPD aspects of projects, with a delivery focus and ability to meet timelines to prespecified quality and cost.

Specialist in tools such as Win Non Lin/Phoenix NLME, Non Mem, Berkeley Madonna, MATLAB, and Sim CYP. Excellent interpersonal and communication skills coupled with strong influence and leadership skills. Providing disciplinary scientific leadership and presenting work through patents, publications and lectures. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions.

That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. At Astra Zeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science.

Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. Empowered to step up, we free ourselves from fear of failure to dig deep into the biology of complex diseases and make bold decisions. Celebrating our successes and failures along the way. Are you ready to embrace new and varied opportunities to develop and learn? Are you ready to be part of a team that makes a bigger impact on patients' lives?

If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. Apply now! Date Posted 06-Dec-2023 Closing Date 05-Feb-2024Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e.

g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

Science In Massachusetts

1
Analytical Chemist / Andover, MA
Andover
Jan 02, 2024
1
Scientist, IPT Electrical Engineering
Andover
Oct 21, 2023
1
Lead Scientist/Team Leader Fireproofing - GCP
Andover
Sep 01, 2023
1
Msat scientist
Andover
Jul 27, 2023
1
Laboratory coordinator
Andover
Jul 27, 2023
1
Bench scientist (contract)
Andover
Jul 28, 2023