Principal Scientist, Translational Bioinformatics

and resources needed to realize unreasonable results. The Role FL97 is seeking an experienced, creative, and talented Senior Scientist or Principal Scientist, Cellular Biology to join our team. You will be part of an agile, cross-functional team responsible for building the mammalian cell culture, cell engineering, and cell-based assay capabilities of our autonomous discovery campaigns.

Together with biologists, machine learning scientists, software developers, and automation engineers, you will work toward building and automating cell-based workflowsacross a variety of valuable applications. All scientists must be willing to learn and use basic Python and/or R programming. The ideal

candidate brings primary expertise in mammalian cell biology, culture, and genetic engineering, with a proven track record of building high quality in vivo assay platforms.

Industry experience in cell therapy, i PSCs, and/or regenerative medicine is a plus. Candidates should have experience and interest in: Cutting edge cell-based assays and automation Mammalian gene editing technology (KO, targeted KI) Nonviral payload delivery using electroporation, Piggy BAC, or other relevant systems Radically new working styles and scientific approaches Learning to code experimental protocols and data analysis workflows in Python In this role, you would: Work in a small, diverse, project-based team

Flexibly react to new information within an agile framework Build novel, robust, working prototypes of engineered biological products Collaborate with machine learning, software, and automation experts Provide hands-on training to Research Associates and computational colleagues Actively shape and plan new projects at regular intervals Working at FL97, you would have access to advanced technology in the areas of: AI experimental design and simulation Automated liquid handling and cell culture Fully digital lab workflows About Flagship Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability.

Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's " Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies.

Learn more about Flagship at . Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, interaction, national origin, interactionual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. At Flagship, we recognize there is no perfect candidate.

If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, " FSP" ) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team.

Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers. /working-with-us. Working with Us: Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a

job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol-Myers Squibb is a global biomedical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. We are passionate about

making an impact on the lives of patients through research. This open position offers the opportunity to join a vibrant and collaborative research community striving to find new disease targets and develop innovative therapies.

We seek a highly motivated, passionate, and collaborative drug hunter with demonstrated experience in oncology discovery biology and preclinical drug development to join BMS in Cambridge, MA. The ideal candidate will have a deep understanding of cancer cell signaling, small molecule drug development, in vivo pharmacology, and translational sciences. Proven ability in therapeutically exploiting synthetic lethal or undruggable vulnerabilities is preferable.

The qualified candidate will lead several drug discovery efforts and work closely with global cross-functional teams, including Target-ID, chemistry, in vivo pharmacology, toxicology, DMPK, and translational biology, to advance novel ideas from concept to the clinic. S/he will supervise a team of associates and biology leads to support their project responsibilities and contribute to team objectives, including but not limited to investigating drug mechanisms of action, assay development, pharmacodynamics readouts, and exploring therapeutic hypotheses. Excellent oral and written communication skills are required, with the ability to thrive in a fast-paced matrix environment.

The successful candidate will have the presentation skills to influence and inform scientific decisions at senior management, cross-functional, or external meetings. They will also have opportunities to develop and foster external partnerships or academic collaborations to advance internal programs, as appropriate. BMS is committed to people development and fosters a learning environment to build scientific and leadership skills. In addition to leading scientific projects, the candidate will also be able to participate in and lead site initiatives and influence broader portfolio, strategic, and business development decisions.

Basic Qualifications: Bachelor's Degree 10+ years of academic and / or industry experience Or Master's Degree 8+ years of academic and / or industry experience Or Ph. D. or equivalent advanced degree in the Life Sciences 6+ years of academic and / or industry experience 2+ years of leadership experience Preferred Qualifications: A Ph. D. degree with a minimum of 8 years of relevant industry experience in preclinical drug discovery and cancer biology. Industry experience will be prioritized over academia.

In-depth knowledge of cancer cell signaling, small molecule drug development, in vivo pharmacology, and translational biology Demonstrated ability to lead a cross-functional drug discovery team and advance preclinical drug discovery from target validation to clinical candidate Strong leadership skills, excellent interpersonal, oral, and written communication skills Demonstrated ability to supervise and support the development of a high-performing team of associates and/or facilitate career progression Demonstrated ability to effectively influence stakeholders and cross-functional leadership in a dynamic, fast-paced matrixed organization Ability to effectively and seamlessly multitask and prioritize across multiple portfolio assets, with complex strategies and accelerated development timelines Demonstrated ability to advise and participate in business development due-diligence evaluations If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway.

You could be one step away from work that will transform your life and career. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as " Transforming patients' lives through science™ " every BMS employee plays an integral role in work that goes far beyond ordinary.

Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to xyz X@.

Visit careers. /eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a medical/ biomedical company, all while maintaining full-time benefits.

Our teams support career growth whether you are looking for long term opportunities within the scientific ladder, to pursue project management, or develop into a leader -- these are just a few career pathways available once your become a part of the Thermo Fisher's Clinical Research Group team. To learn how Thermo Fisher's Clinical Research Group can advance your career, apply now! Essential Functions: Perform testing in a

GMP lab and follow all applicable SOPs and STMs when performing the tests. Perform colorimetric 96-well plate-based tests such as anthrone, uronic acid, BCA, biotin, free polysaccharide.

Perform HPLC and SEC-MALS analysis. Participate in the method qualification, validation, transfer as necessary. Perform trending of QC assays, reagents, assay controls, system suitability, standards. Perform release and stability testing. Participate in the qualification and management of critical reagents, reference standards. Assist in preparing SOP's, technical protocols, reports, OOS/OOT/deviation investigations. Work with QC management in data analysis, peer review of analytical data. Work with the

QC team to maintain and update inventories. Monitor controlled temperature units.

Supporting initiation of stability studies and pull stability samples. Work collaboratively with different teams and groups. Perform additional duties and projects as assigned by the QC management. Education and Experience: Bachelor's degree in Chemical Engineering, Chemistry, Biology or Scientific Field, or equivalent and relevant formal academic / vocational qualification Previous industry experience that provides the knowledge, skills, and abilities to perform the job comparable to 2+ years In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Preferred Experience: 2+ years of GMP QC testing experience Knowledge, Skills, and Abilities: A basic knowledge of c GMPs HPLC or CE Testing experience Experience with biorelevant dissolution testing The ability to work successfully in both a team/matrix environment as well as independently The ability to work in a fast pace environment, manage priorities, and maintain timelines for multiple projects Self-motivated, organized and detail oriented Working Environment: Thermo Fisher Scientific Clinical Research Group values the health and wellbeing of our employees.

We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role: Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. Able to work upright and stationary and/or standing for typical working hours. Able to lift and move objects up to 25 pounds Able to work in non-traditional work environments. Able to use and learn standard office equipment and technology with proficiency.

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment. Our 4i Values: Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us.

As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #Start Your Story with PPD, part of Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued. Apply today! http: //jobs. Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, interaction, interactionual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Accessibility/Disability Access Job Seekers with a Disability: Thermo Fisher Scientific offers accessibility service for job seekers requiring accommodations in the job application process. For example, this may include individuals requiring assistance because of hearing, vision, mobility, or cognitive impairments. If you are a job seeker with a disability, or assisting a person with a disability, and require accessibility assistance or an accommodation to apply for one of our jobs, please submit a request by telephone at -xyz X.

Please include your contact information and specific details about your required accommodation to support you during the job application process. This telephone line is reserved solely for job seekers with disabilities requiring accessibility assistance or an accommodation in the job application process. Messages left for other purposes, such as not being able to get into the career website, following up on an application, or other non-disability related technical issues will not receive a response.

with computational biologists, immunologists, and translational biologists in Oncology Research support cancer vaccine discovery, translational research, and clinical development. Here's What You'll Do Identify immunogenomics datasets and tools (such as IEDB, IMGT) and build analytical solutions for oncology target identification and design Using public and proprietary sequencing datasets, design and interpret bioinformatics analysis to derive insights for biological hypothesis and biomarker discovery Stay up to date with current state-of-the-art practices of multi-omics data analysis and interpretation, particularly in the fields of cancer immunogenomics Collaborate closely with computational

and experimental biologists to support oncology research and clinical development Here's What You'll Need (Minimum Qualifications) Ph.

D. in Bioinformatics, Computational Biology, Systems immunology, or related quantitative discipline Minimum 2 years Bioinformatics, Computational Biology, or related experience in industry Experience with -omics data analysis, including RNA-seq, WES, immune repertoire sequencing Strong coding skills with R and/or Python Experience with high performance computing and AWS cloud computing platform Here's What You'll Bring to the Table (Preferred Qualifications) Prior experience leading the development and productization of prediction algorithms, ideally in

the bioinformatics space Strong problem-solving skills and a results-oriented mindset Demonstrated cross-functional collaboration with multidisciplinary teams Curious about exploring a new pathway for drug discovery Be bold in proposing and delivering on creative experimental designs and ideas Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including: Highly competitive and inclusive medical, dental and vision coverage options Flexible Spending Accounts for medical expenses and dependent care expenses Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities Family care benefits, including subsidized back-up care options and on-demand tutoring Free premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipment Adoption and family-planning benefits Dedicated care coordination support for our LGBTQ+ community Generous paid time off, including: • Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafter Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning tools Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options Complimentary concierge service including home services research, travel booking, and entertainment requests Free parking or subsidized commuter passes Location-specific perks and extras!

About Moderna Since our founding in 2010, we have aspired to build the leading m RNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U. S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit /careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is proud to be an equal opportunity workplace and is an affirmative action employer. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, interaction, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, interactionual orientation, marital or familial status, or any other personal characteristic protected under applicable law.

Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at xyz X@. (EEO/AAP Employer) #LI-JL2