Location: Brookings, SD
Company: Prairie Aquatech
upgrading plant-based commodities, such as soybean meal, to sustainable, high-quality ingredients. Our company is currently experiencing rapid growth and we are seeking an Analytical Chemist to join our team. The Analytical Chemistry will assist with a variety of experiments and tests under the supervision of the project leader.
Specific areas of work will include chromatography, spectroscopy, feedstock composition chemistry, protein chemistry and enzymes assay. The R&D work will focused on carrying out experimental designs and assisting in data collection and analysis. Responsibilities Chromatography: Familiarity with carbohydrate quantification using high pressure liquid chromatography
(HPLC). Previous experience with soy carbohydrates: stachyose, raffinose, sucrose, glucose, fructose, galactose, etc. Protein Chemistry: Protein run internally on LECO.
Knowledge of amino acid chemistry, protein dispersibility index, and molecular weight distribution. Previous experience with SDS-PAGE. Feedstock Composition Chemistry (fat, fiber, ash, phytic acid, etc) Fiber: Familiarity with crude fiber, NDF, and ADF and methods to differentiate. Assays & Enzymes: Ability to perform assays for quantifying protein and sugar metabolism. Familiarity with carbohydrases and proteases. Mass Balance: Strong understanding of mass balance. Operating and maintaining lab equipment, as well as analytical
instruments Setting-up and performing wet chemistry experiments Producing and effectively communicating reliable and precise data to support R&D and manufacturing operations.
Recording laboratory data in accordance with company's policy. Provide technical guidance / trouble shooting where applicable. Make and record observations, perform calculations, collect and prepare data for evaluation by team on a weekly basis. Conduct support functions with team members such as stocking and distributing supplies and equipment. Carry out all laboratory functions in accordance with Good Laboratory Practices, all Company Policies and Procedures as well as applicable regulatory standards.
Additional responsibilities will include assisting with laboratory purchasing, developing and maintaining inventories of chemicals and supplies, and waste management. Required Qualifications: Bachelor's Degree in Analytical Chemistry, Biochemistry or related field of study. Minimum 2 years of industry experience operating and maintaining lab equipment and analytical equipment Experience performing laboratory testing, samples collection and analyses. Scientific, yet practical approach to problem solving. Strong understanding of scientific methodologies. Strong written and verbal communication skills.
Proficient in Microsoft Word, Excel and Power Point Ability to work on cross-functional teams and to prioritize and manage multiple demands. Job Location: Brookings, SD Job Posted by Applicant Pro
Medgene Labs has a single mission: To be a world-class Immunological Services Provider™ for leading livestock producers and their veterinarians. POSITION SUMMARY A Research and Development (R&D) Post License (level depending on experience) will be responsible for performing experiments and tasks in support of R&D projects involving vaccine research for various diseases in multiple species to address customers' needs.
In particular, the scientist will be responsible for conducting, modifying, and developing immunological assays, as well as support of other teams within R&D and throughout the company. The position requires the ability to perform detail-oriented work and successfully integrate
within a strong R&D team. The scientist will report to the R&D Post License Manager and will not have direct reports. JOB DUTIES Perform in both an individual and team setting.
Process clinical samples according to protocol with a high level of detail/accuracy Perform laboratory experiments according to a written method (with supervision level commiserate to experience) Designs and executes experiments (with supervision level commiserate to experience) Perform data analysis, troubleshooting, data presentation and discussion. Perform basic microscopy. Ability to learn and utilize software for set tasks including but not limited to Smartsheet, Compass, Soft Max, Gen5 Treat experiments and
data with a high level of integrity and ethics Able to follow detailed instructions, scientific protocols, and Standard Operating Procedures Strong understanding and application of aseptic technique, biosafety level requirements, and strong adherence to biosecurity practices Keep laboratory documents and logs as needed following ALCOA+ principles.
Maintain quality control checks and a safe environment in compliance with all governmental and laboratory policies, rules, regulations, and codes. Trains other scientists as appropriate for their knowledge and skill level Performs routine laboratory maintenance and upkeep, including cleaning glassware, autoclaving, waste disposal, and equipment maintenance/monitoring as necessary.
Performs literature searches to bring in new techniques or improve current assays. Coordinates with various teams within R&D as well as teams external to R&D Perform other duties as needed. MINIMUM QUALIFICATIONS: Bachelor's degree from an accredited university in microbiology, virology, molecular biology or related field. Knowledge of: General laboratory principles and equipment Biosafety (BSL1 / BSL2) and biosecurity practices Immunological methods and techniques involving both live and inactivated cultures. Cell culture methods including cryopreservation.
Viral propagation techniques and identification Bacterial propagation techniques and identification Microsoft Word and Excel computer skills Ability to: Perform various cell culture growth methods, tests, and analyses. Follow detailed directions and instructions. Work safely with dangerous and contagious materials and specimens. Operate general lab equipment and computers. Perform mathematical computations. Interpret subject matter. Establish and maintain effective working relationships with others. Perform various tests and adapt techniques as required.
Maintain accurate and up-to-date laboratory notebook records. Communicate information clearly and concisely. Job Posted by Applicant Pro
has a single mission: To be a world-class Immunological Services Provider for leading livestock producers and their veterinarians. Medgene is seeking to hire a Process Development and Improvement Associate Scientist for our rapidly growing business and product pipeline.
Purpose: Perform process development and improvement studies as directed by the Process Development and Improvement Leader. Distinguishing Feature: The Process Development and Improvement Associate Scientist is responsible for executing process development and improvement studies for the manufacture of recombinant proteins. The position requires the ability to write, read, and understand standard operating procedures and
be able to execute the procedures to ensure compliance with CVB regulations. Good documentation practices are required while documenting the work that is being performed.
Functions: Read and understand SOPs and Protocols for manufacturing vaccines. Maintains records detailing adherence to established policies. Execute experiments in small scale bioreactors and fermenters to optimize expression and product quality of recombinant biologics. Maintain detailed and accurate laboratory notebooks/batch records. Have proven hands on experience in aseptic techniques. Perform production of buffers, growth media, and solutions. Help maintain laboratory equipment, supplies, and a clean/safe working
environment. Assist with production activities as needed. Work with Production on transfer of products.
Manufacturing of veterinary vaccines in compliance with CVB guidelines and regulations. Maintains appropriate records commensurate with CVB guidelines. Ensures high-quality production standards from culture through bottling. Ensure security of Master Seed, Unreleased, and Released Products. Assist with creating the conditions for increasing productivity by analyzing and improving existing processes as well as improving technology transfers and minimizing losses. Performs other work as assigned. Reporting Relationships: Reports directly to the Process Development and Improvement Leader.
Indirectly reports to the VP of Manufacturing. Challenges and Problems: Challenged to provide effective, safe vaccines to commercial clients in a timely manner. Assist with investigations into poorly-growing cultures, inefficient yields, processing problems. Keeping of detailed records will be an absolute necessity, subject to Audit by the Regulatory and Compliance Officer and Quality Assurance. Decision-Making Authority The Process Development and Improvement Leader is responsible for making experimental decisions involved in the efforts of the position in order to deliver accurate, concise, and timely data.
Decisions may also be delegated to Process Development and Improvement Leader by the Vice President of Manufacturing. Contact with Others: Daily contact with manufacturing, QA, QC, Regulatory, and R&D personnel. Limited contact with Sales and Marketing. Working Conditions: Potential for exposure to human and animal pathogens, including blood-borne pathogens. Exposure to infectious agents, dangerous chemicals, high-voltage equipment, toxic fumes, high-pressure steam, temperature extremes, and potential mutagens. Knowledge, Skills, and Abilities: Knowledge of: BS in Biochemistry, Biology, or equivalent.
Previous experience with fermentation and/or cell culture, chromatography, or other downstream processing techniques. Basic level knowledge and understanding of 9CFR. Basic level knowledge and understanding of hazardous material handling. Aseptic Techniques and good laboratory practices. Good Documentation Practices. Ability to: Follow specific procedures. Work safely with infectious materials and specimens. Operate scientific equipment and computers. Establish and maintain effective working relationships with others. Keep detailed and accurate documentation.
Maintain a safe work environment for self and other employees at all times. Job Posted by Applicant Pro
precisely than previously possible. Medgene Labs has a single mission: To be a world-class Immunological Services Provider for leading livestock producers and their veterinarians. Purpose: Medgene Labs is seeking a Research Scientist to join our growing team and help fully develop our construct bank for viral and bacterial expressed proteins.
The candidate will serve as technical support, providing molecular engineering experience. Primary focus will be to perform daily laboratory assays, maintenance, and optimization of procedures. Distinguishing Feature: The Research Scientist is responsible for support within the Construct Team. Must have a strong background in molecular and immunological
assays, protein production and optimization, and bioinformatics. Coordination and cooperation with Construct Team, Immunological Services, Production, and Quality Assurance departments are essential.
The position requires independent judgement and interpretation under the direct supervisor. Candidates should have a minimum of a Bachelor of Science in Microbiology/Chemistry/Animal Science or related field. Experience preferred, but not required. Functions: Perform molecular cloning efforts by applying molecular biology techniques. Characterization of vaccine candidates by performing molecular biology techniques. Operate and maintain laboratory and experimental equipment. Work collaboratively
with other team members to accomplish project goals and milestones.
Track and document results with Official Documents and Laboratory Notebooks. Creating the conditions for increasing productivity by analyzing and improving existing processes. Monitoring Compliance with aseptic procedures and cleaning schedules as well as occupational health and safety regulations. Ensuring a culture of safety for all employees at VST/Medgene. Performs other work as assigned. Reporting Relationships: Typically reports to the Constructs and Process Development Director, and may provide work direction to Associates, Technicians, and/or students or other staff assigned to the laboratory.
Challenges and Problems: Challenges include performing within established timelines, maintaining accuracy, and consistency due to variance in constructs. Keeping of detailed records will be an absolute necessity, subject to audit by the Regulatory and Compliance. Problems include potential weekend and off-hours work. Decision-Making Authority Decisions include development of specific assays, interpretation of data and communication to appropriate department; what supplies to order; safety and accuracy of equipment; the identity of reference reagents and tests; sources of testing problems; when to contact supervisors for assistance; whether to call service for a piece of equipment; informing management of status of vaccine serials.
Contact with Others: Daily contact with junior technicians, additional staff of VST/Medgene. Working Conditions: Potential for exposure to human and animal pathogens, including blood-borne pathogens. Exposure to infectious agents, dangerous chemicals, high-voltage equipment, toxic fumes, high-pressure steam, temperature extremes, and potential mutagens. Knowledge, Skills, and Abilities: Knowledge of: The methods and techniques of bacterial, viral, mammalian and insect cell culture.
Baculovirus expression vectors and protein production Molecular techniques including transfections, cloning, DNA/RNA extraction and PCR, restriction enzyme digestion Common biochemical and immunological techniques, including SDS-PAGE, UV/Vis spectroscopy, ELISA and western blotting. Laboratory quality controls procedures and appropriate statistical methods. Ability to: Perform various cell culture growth methods, tests, and analyses. Follow specific procedures Work safely with infectious materials and specimens Operate scientific equipment and computers Write detailed SOPs and protocols Identify reference materials Establish and maintain effective working relationships with others Perform various tests, adapt techniques as required, and perform complex computations.
Prepare scientifically accurate and thorough reports. Medgene Core Competencies Accountability and level of Impact Plans and leads completion of project work with team Works autonomously; manages resources; consults with and updates supervisor Technical/Functional Expertise & Application Applies broad knowledge and specialized training in complex scientific principles and techniques Modifies existing processes, procedures and technologies, or develops new ones, as needed May provide training, or technical consultation to others Problem Solving and Innovation Applies methodology and creativity to resolve complex problems to individual accountabilities and project teamwork.
Communication, Collaboration, and People Influence Proactively collaborates and shares information/ better practices within and across Medgene teams, units and departments to influence at the site level. Produces internal written communications; provides input to publications for external use; facilitates team meetings; presents in project teams. Job Posted by Applicant Pro
has a single mission: To be a world-class Immunological Services Provider for leading livestock producers and their veterinarians. Medgene is seeking to hire an R&D Analytical Development Associate Scientist for our rapidly growing business and product pipeline.
Purpose: Perform daily operations within the R&D Analytical Development team. Distinguishing Feature: The position is responsible for developing new analytical assays for use in R&D or QC manufacturing. The analytical team also serves as a resource for troubleshooting or reoptimizing existing assays in R&D or QC manufacturing. Knowledge of basic laboratory procedures within an analytical laboratory and aseptic techniques are required.
Previous experience with immunological assays (including ELISA, Western Blots or Serology) is preferred. Experience with automated Western Blot technology is a plus.
The position requires the ability to read and understand standard operating procedures and be able to execute the procedures to ensure compliance with CVB regulations. Good documentation practices are required. Functions: Assist in design, optimization, and validation of immunological assays for use in R&D and QC manufacturing. Assist in troubleshooting of issues that may arise with current immunological assays. Read and understand SOPs and Protocols for manufacturing vaccines. Maintains records detailing adherence to established
policies. Maintains appropriate records commensurate with CVB guidelines.
Maintenance of laboratory equipment, facility, and standards within the Analytical team. Ensure compliance with aseptic procedures and cleaning schedules. Performs other work as assigned. Reporting Relationships: Reports directly to Analytical Manager. Challenges and Problems: Challenged to develop and validate assays used for quantification of proteins in an independent setting. Assist with different problems such as mechanical/equipment failure, contamination, or poorly growing cultures. Keeping of detailed records subject to Audit by the Regulatory and Compliance and Quality Assurance, will be an absolute necessity.
Decision-Making Authority Decisions will be made in conjunction with Analytical team. Contact with Others: Daily contact with R&D, Manufacturing, QA, and QC personnel. Limited contact with Regulatory, Sales and Marketing, personnel. Working Conditions: Potential for exposure to human and animal pathogens, including blood-borne pathogens. Exposure to infectious agents, dangerous chemicals, high-voltage equipment, toxic fumes, temperature extremes, and potential mutagens. Knowledge, Skills, and Abilities: Knowledge of: Immunological assays used for quantification of proteins.
Aseptic Techniques and good laboratory practices. Good Documentation Practices. Experience with ELISA, Western Blot or other immunological assays preferred. Ability to: Develop and follow specific procedures. Work safely with infectious materials and specimens. Operate scientific equipment and computers. Establish and maintain effective working relationships with others. Keep detailed and accurate documentation. Maintain a safe work environment for self and other employees at all times. Job Posted by Applicant Pro
