Location: Boston, MA
Company: Takeda Pharmaceutical
About the role: At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
The vision of Takeda is to build a world-class Cell Therapy team and deliver allogeneic innate cell therapy product to bring hope to both hematological and solid tumor patients. Oncology Cell Therapy Innovation is missioned to develop innovate innate cell platform and novel engineering approaches to drive discovery pipeline for Takeda Cell Therapy
The Oncology Cell therapy Innovation team is seeking experienced molecular biologist who has a background in cancer immunology, genetic engineering especially non-viral mediated gene editing.
-As a senior member of the team, you will play an important role in optimizing cell therapy platforms, e. g. CAR-NK, CAR-----T, to improve the biological function (potency and persistence) of cell therapy products, based on solid understanding of innate cell biology, cancer/immune biology in tumor microenvironment and genetic engineering. You will lead discovery projects and collaborate with colleagues within department and cross-function teams to drive the development of Cell Therapy discovery platforms.
How you will contribute: Contribute to discovery projects by independently designing and developing well-defined mechanistic experiments and projects within oncology cell therapy research.
Lead from the lab to advance novel and differentiated cell therapy products toward clinical milestones, by working collaboratively with internal cross-functional teams and external partners. Design, execute, and interpret functional -in vivo, -in vitro, and -ex vivo -assays to understand the mechanism-of-action and play an active role in subsequent scientific discussions to drive decisions. Propose novel projects based on internal results, external partners, and published reports and demonstrate leadership through communication of study plans/value, and research results Skill and breadth of knowledge in a scientific field Stay current with scientific development (e.
petitive landscape, new technology, new research portfolio, and new partnership) Scientific leadership and establish rigorous standards for execution effectiveness Have managerial responsibility Independently control workload and demands Scientifically independent Scientific driver for research strategy that impacts group internally and outside area of function Initiate and lead external interactions and collaborations Frequent contact with internal and external personnel at multiple management levels Elect approaches for new tasks and provide strategic project recommendations Minimum Requirements/Qualifications: Ph.
D. in Immunology, Biology, Genetic Engineering, or related discipline. Minimum of 6+ years relevant medical industry/academic experience post-graduation Hands on experience with CRISPR-, transposon-mediated genome engineering in multiple cell types. Independently design sg RNAs, constructs for KO and KI through non-viral (plasmid, self-replicating vectors, EP, LNP) methods.
Profound skills in analytical methods such as flow cytometry, dd PCR, real-time PCR, off-targets evaluation, NGS etc. Previous experience with CAR-T, CAR-NK, CAR-----T, TCR-T cell immunotherapies, including cell culture, immune cell activation/expansion, viral transduction in vitro and in vivo immune cell characterization and function backssment, such as, multi-color flow immunophenotype, multiplex cytokine measurement, cytotoxicity assay is a plus Excellent written and verbal communication skills, detail-oriented organization skills, and team collaboration skills. Track record of publications to demonstrate scientific establishment.
What Takeda can offer you: Comprehensive Healthcare: Medical, Dental, and Vision Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan Health & Wellness programs including onsite flu shots and health screenings Generous time off for vacation and the option to purchase additional vacation days Community Outreach Programs and company match of charitable contributions Family Planning Support Flexible Ways of Working Tuition reimbursement More about us: At Takeda, we are transforming patient care through the development of novel specialty medicals and best in class patient support programs.
Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.
EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, interaction, interactionual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations Boston, MAWorker Type Employee Worker Sub-Type Regular Time Type Full time
Boston, Massachusetts, this law firm focuses on biotechnology, chemistry, and medicine to deal with complex issues of intellectual property. The firm also focuses particularly on technology licensing, patent prosecution, corporate and investment diligence, patent portfolio management, and freedom-to-operate analysis.
This firm has represented different types of clients including medical centers, universities, and all sizes of corporations. This firm represents clients in technological innovation and scientific discovery. Additional Skills: The candidate should possess excellent analytical and communications skills; must think, write, and speak clearly.
The optimal project outcome will see the new assay(s) implemented in Selux's second-generation AST platform in addition to publications. The successful candidate will work closely with Selux's senior scientists and engineers, have direct access to Selux's esteemed scientific and clinical advisors, and build industry and academic partnerships necessary to make the project successful.
We are looking for a candidate with experience working with bacteria and assay development, including use of time-resolved Forster resonance energy transfer (TR-FRET), fluorescence polarization/anisotropy. Selux Diagnostics' platforms will enable clinicians to administer personalized therapies to Infectious
Diseases patients within hours rather than days. These advances promise to improve patient care, shorten hospital stays, and combat the growing antibiotic resistance epidemic.
Selux's NGP AST platform offers uncompromised accuracy and an unprecedented speed to results and breadth of menu. The company's Grow-on-the-Go Blood Culture system completes the microbiology laboratory transformation by slashing the time to culture positivity for all samples and incubation during sample transport for integrated health networks. The 35-person company is funded with a combination of Federal and private investment and will begin FDA trials on its initial NGP AST product in this quarter (Q1-2020). The
ideal candidate will have/be: A Ph D in Microbiology, Biochemistry, Molecular Biology, Biomedical Engineering or a related field Experience performing phenotypic assays on bacteria Experience working with a variety of bacterial species Experience developing no-wash assays Experience performing TR-FRET and/or fluorescence polarization A desire to learn industrial R&D and see his/her work come to fruition in a product A desire to continue publishing An independent thinker and problem-solver, who is an enthusiastic and collaborative professional Excellent written and oral communication skills and proven ability to work well in a team environment Passion about an early-stage start-up that aims to change industry and how healthcare is delivered!
recblid 30k3bj2puip0ojss7rrj9os3kdftk0 Ph. D.
massively parallel computation. We're seeking a motivated Associate Computational Biologist with an interest in synthetic biology to join our interdisciplinary team and contribute to the development of CATALOG's DNA-based data storage and computation platform.
In this role, you will: Build custom software tools to backss DNA sequencing metrics Assist research and development activities for developing bioinformatics pipelines Support the translation of new technology from bench protocol to a fully automated solution at scale with cloud-based software tools Collaborate with hardware and software teams to implement new software tools to backss the end-to-end platform performance Analyze
NGS data, present findings, and make recommendations to internal and external stakeholders Continuously backss current literature for innovation opportunities We are looking for someone with experience in the following areas: Programming with Python and C/C++, in a Linux environment, and with relevant tools Understanding of molecular biology with an emphasis on nucleic acid chemistry Experience with and understanding of NGS platforms and software tools Experience interfacing with computation platforms via the Unix CLI in both commercial (Azure, GCP, AWS) and academic settings Experience with long-read, solid-state, and/or protein sequencing is preferred Familiarity with lab automation, though
not required, is a plus We are looking for someone driven by: The excitement of building novel tools and technologies at the intersection of synthetic biology and engineering The opportunity to contribute to a supportive and collegial team with a growth mindset The challenge of teaching and learning from colleagues of diverse academic/industry backgrounds The prospect of wearing many hats as we pioneer the future of DNA-based data storage and computation You will also need to be able to: Thrive in a fast-paced environment Exhibit creativity and proactivity in problem-solving Collaborate effectively in small, cross-disciplinary teams Be a dependable team player with strong verbal and written communication skills Plan and execute tasks independently We are looking for someone with: A B.
S. or M. S. in computational biology, molecular biology, biomedical engineering, or a related discipline, coupled with ideally with 1+ years of industry experience, showcasing a strong academic and practical background Breadth of experience in and ability to design and build DNA sequence analysis software tools from conceptualization to implementation At CATALOG, we empower you to think critically, work creatively, and conquer uncharted problems in a groundbreaking field.
We prioritize building an inclusive team that embraces diverse viewpoints, supports workforce diversity, and offers competitive compensation packages, including medical, dental, and vision insurance, 401(k) with company matching. Please note, visa sponsorship is not available for this positio Powered by Jazz HR
including 105A CMR 725 and 935 CMR 500. The Retail Associate position is designed to provide the people that we serve with a consultative buying experience to consistently provide a transformative guest experience by making every effort to partner with each guest to find the best available.
Responsibilities: Assist qualifying patients and caregivers and adult use guests in obtaining their cannabis/cannabis infused or medicated products Participate actively in ongoing training in customer service delivery Assist with dispensary opening and closing, to include the protection of dispensary assets by following Temescal Wellness operational policies and procedures Compliance with program regulations
as they relate to retail operations and to the dispensing of medicated products, including the use of seed to sale software Maintenance of a well-stocked and beautifully merchandised dispensary Uphold all standards pertaining to dispensary cleanliness and Serv-Safe for infused product handling Consistently provide a transformative guest experience by making every effort to partner with the guest to find the best available product for their stated need Maintain store security, including building security and the security of all company assets to include the handling of cash and other financial instruments All other duties assigned by management This job posting is intended to describe the general
requirements for the performance of this role.
It is not a complete statement of duties, responsibilities or requirements. The role of the PSA will expand and evolve based upon the needs of the organization and the demands of our guests. Requirements: Authentic passion to serve the qualifying patients and caregivers of the state of Massachusetts, as well as adult use guests Affinity for handling multiple demands simultaneously and proficiency with time management Ability to learn and to use seed to sale POS software in compliance with program regulations Strong attention to detail High-energy, enthusiasm and positivity, a general can-do spirit Exemplary customer service skills as observed by supervisors and as validated by guest and patient feedback Ability to actively listen to guests and to assist in guiding their product choices.
Thorough knowledge of all program guidelines and relevant Temescal Wellness policies and procedures Strong verbal and written communication skills Ability to visually examine products for quality and signage/labeling accuracy Exhibit a " can-do" attitude and a willingness to take on new responsibilities and tasks as they become necessary Ability to assure compliance by demonstrating attention to detail and the aptitude to process and internalize a large volume of information, most specifically around state regulations Relentless pursuit of accuracy and of achieving efficiency through technology and scalable processes Bilingual in English/Spanish or English/Portuguese is a plus Essential Job Functions: Ability to stand and walk for extended periods of time Bend and stoop to grasp objects, bend and twist neck and waist, reach above and below shoulders and squat Bend and lift loads, not to exceed 50 pounds Repetitive use of hands for grasping, pushing, pulling and fine manipulation Compensation and Benefits: Starting wage: $17.00 - $18.00 per hour Employer pays approximately 70% of medical, dental and vision insurance, including for family members Generous time off policy Mission-driven organization with an excellent work-life balance This position is not eligible for visa sponsorship.
Temescal Wellness is committed to creating a diverse environment and is proud to be an Equal Opportunity Employer. We are committed to fair hiring practices and to creating a welcoming environment for all team members. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, interactionual orientation, national origin, genetics, disability, age, or veteran status.
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Boston, Massachusetts, this law firm focuses on biotechnology, chemistry, and medicine to deal with complex issues of intellectual property. The firm also focuses particularly on technology licensing, patent prosecution, corporate and investment diligence, patent portfolio management, and freedom-to-operate analysis.
This firm has represented different types of clients including medical centers, universities, and all sizes of corporations. This firm represents clients in technological innovation and scientific discovery. Additional Skills: The candidate should possess excellent analytical and communications skills; must think, write, and speak clearly.
The optimal project outcome will see the new assay(s) implemented in Selux's second-generation AST platform in addition to publications. The successful candidate will work closely with Selux's senior scientists and engineers, have direct access to Selux's esteemed scientific and clinical advisors, and build industry and academic partnerships necessary to make the project successful.
We are looking for a candidate with experience working with bacteria and assay development, including use of time-resolved Forster resonance energy transfer (TR-FRET), fluorescence polarization/anisotropy. Selux Diagnostics' platforms will enable clinicians to administer personalized therapies to Infectious
Diseases patients within hours rather than days. These advances promise to improve patient care, shorten hospital stays, and combat the growing antibiotic resistance epidemic.
Selux's NGP AST platform offers uncompromised accuracy and an unprecedented speed to results and breadth of menu. The company's Grow-on-the-Go Blood Culture system completes the microbiology laboratory transformation by slashing the time to culture positivity for all samples and incubation during sample transport for integrated health networks. The 35-person company is funded with a combination of Federal and private investment and will begin FDA trials on its initial NGP AST product in this quarter (Q1-2020). The
ideal candidate will have/be: A Ph D in Microbiology, Biochemistry, Molecular Biology, Biomedical Engineering or a related field Experience performing phenotypic assays on bacteria Experience working with a variety of bacterial species Experience developing no-wash assays Experience performing TR-FRET and/or fluorescence polarization A desire to learn industrial R&D and see his/her work come to fruition in a product A desire to continue publishing An independent thinker and problem-solver, who is an enthusiastic and collaborative professional Excellent written and oral communication skills and proven ability to work well in a team environment Passion about an early-stage start-up that aims to change industry and how healthcare is delivered!
recblid 30k3bj2puip0ojss7rrj9os3kdftk0 Ph. D.
