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11,419 results match your filters
POPULAR
Senior Scientist - TCR Gene Therapy
1
Senior Scientist - TCR Gene Therapy
Washington, DC
Dec 16, 2023
POPULAR
Senior Scientist, In Vivo Pharmacology, Oncology Research
1
Senior Scientist, In Vivo Pharmacology, Oncology Research
Washington, DC
Dec 16, 2023
POPULAR
Sr. Principal Scientist Job
1
Sr. Principal Scientist Job
Alabaster, AL
Dec 16, 2023

the world’s leading supplier of solid rocket motors, a leading provider of launch vehicles, satellites and other space systems, and the nation’s largest manufacturer of ammunition. Orbital ATK is currently seeking an experienced Sr. Principal Scientist to provide leadership to our Research and Lab team in our Promontory, Utah offices.

Role description & Responsibilities: The Sr. Principal Scientist is responsible for development, scale-up, manufacture and test activities of propellants and explosives at the Promontory facilities. Incumbent will be expected to interface with management and customers on proposals, program status, and technical accomplishments. Job Duties: • Conducting analyses

then writing reports and/or presenting conclusions and recommendations • Consulting with engineers, scientists, program and project managers • Presenting to customers, program managers, management and design teams • backssing reliability, probability, and technical decisions based on statistical methods Experience Requirements: • Candidate must have a minimum of 5 years of Physical-Organic Chemistry experience.

• Must be able to obtain a Secret clearance Experience Preferred: • Experience in thermochemical and combustion analysis • Demonstrated experience in melt-pour, pressure casting, and granulation and pressing • Knowledge and demonstrated experience in polymer chemistry and decomposition

reaction mechanisms, manufacturing process control and methodologies, facility and process design, and hazards characterization Skills & Qualifications: • Excellent written and oral communication skills • Excellent time management and organizational skills • Detail oriented but able to understand the big picture • Broad understanding of statistical methods and their application in aerospace • Strong knowledge rocket motors, flares, aerospace vehicles and components • Extensive experience with design of experiments, SPC, variance analysis, Monte Carlo methods • Strong skills in a wide variety of statistical methods and their application • Excellent written and oral communication skills Education/Certifications • BS degree in Chemistry or Chemical Engineering or related field required.

BS degree with 10 years experience, or MS degree with 7 years experience, or Ph D with 5 years experience Position may be filled at a lower level (Principal Scientist) • BS Degree in Chemistry or Chemical Engineering with 7 years experience, or MS degree with 5 years experience, or Ph D with 2 years of experience If you are a dynamic, successful, driven professional, Orbital ATK is the company that will further your experience and career growth. We offer a highly competitive salary, comprehensive benefits including, medical, dental, 401k, tuition reimbursement, and much more.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, interaction, national origin, disability status, protected veteran status, or any other characteristic protected by law. Equal Opportunity Employer M/F/V/D Are you a Veteran? Visit our Jobs for Veterans page to find jobs that match your military background. Orbital ATK Flight Systems Group provides products and services that span the launch, missile systems and aerospace markets.

We are a premier producer of solid rocket propulsion systems and specialty energetic products; a leading provider of small and medium class space launch vehicles for Civil, Do D and Commercial missions; a major supplier of interceptor boosters and target vehicles for missile defense; and a world class manufacturer of composite primary and secondary structures for commercial and military aircraft and launch vehicles.

POPULAR
Project Manager
1
Project Manager
Bethesda, MD
Dec 16, 2023

at a diverse and vibrant NIAID worksite to directly support ongoing research activities as a contractor team member. Take the next big step in your career and apply below to help us make a difference. CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services.

We combine our proven systems with today's most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global

health security; and HIV/AIDS programs. Our employees enjoy a diverse, collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad.

Responsibilities Develop high-quality written materials derived from analysis of data and information. Assist and work collaboratively with the OGR Regional Officers and other staff to support the management of research resources, technical administration, and programmatic evaluation of funded grants and other activities. Independently, use electronic databases to conduct comprehensive programmatic analyses based on specific and/or general parameters and summarizes

information, draw conclusions and provide recommendations to advise program staff on issues related to the program.

Work closely with the OGR Regional Officers to facilitate all activities related to regional portfolios, including to develop region-specific research initiatives and serve as a backup to the program staff for activities related to the regional portfolios. Provide support, comprehensive coordination, and reporting for meetings and committees coordinated by OGR, under the guidance of OGR Regional Officers, to include scheduling presenters, sending meeting invitations, maintaining participant list, developing agendas, and preparing meeting minutes.

Written materials are developed in accordance with OGR standards and require only minimal review. Draft written materials to disseminate information related to OGR, NIAID, and global research, to include drafting and coordinating of all relevant documentation, assistance scheduling, and planning working groups meetings, coordination of reporting, and tracking all activities through the upkeep of dedicated Share Point sites. Electronic communications are appropriately cleared and disseminated to the relevant parties. Provide subject matter expertise on NIAID international data, the Global Research Affairs Database System, and the Foreign Award and Component Tracking System.

Assist with the performance of secretariat functions in relation to bi-lateral agreement programs including the coordination and arrangement of meetings and workshops, synthesizing annual reports, and serving as a rapporteur. Prepare Power Point presentations for all program staff and for senior NIAID staff. Possess a high operational level in Power Point to work independently developing high quality presentations and has the ability to synthetize information to develop slides. Develop high-quality, visually appealing slides within NIAID standards.

Prepare reports, meeting minutes, analyses, background materials, position papers, talking points, briefing documents, and other materials to support NIAID's global health activities and interests for NIAID, NIH, HHS, and USG officials and for external audiences. Written products are of high quality, developed using thorough analytical skills, and require only minimal revision. Facilitate internal clearance of such documents. Prepare a variety of correspondence, agreements, and science-related documents for signature from the appropriate officials. Assist in the liaison with HHS, CDC, other US Government agencies, foreign officials, and institutions for the coordination and support of OGR programmatic activities.

Assist in organizing and coordinating cross-cutting NIAID international activities. Assist in developing and conducting evaluations of international research programs. Prepare final reports and presentations of results. Assist in identifying ideas for improving the efficiency and effectiveness of office programs, procedures, and operations. Attend meetings that discuss a wide range of research, administrative, and technical topics related to the activities of OGR and NIAID and provides written and oral reports to OGR staff.

Qualifications BS degree is required; MS or MPH is preferred. Minimum of two (2) years of relevant experience preferred. Experience with Microsoft Office Suite, including Word, Excel, Share Point, Teams, One Drive, software products required. Expertise in Microsoft Power Point is required. Excellent interpersonal, oral and written communication skills required. Excellent analytical skills with a high-level of attention to detail are required. Ability to work independently to produce high-quality products and manage processes from start to finish with minimal revisions.

Familiarity with NIH and biomedical research supported by the U. S. Government is highly desirable. Ability to synthesize reports to extract information relevant to a project, topic of interest, or purpose. Expertise with the management of research resources including technical administration and programmatic evaluation of grants. Expertise conducting analyses to draw sound, accurate conclusions from information and data. Exhibit a high-level of attention to detail that is represented in all work products and possess analytical skills to draw sound, accurate conclusions from information and data.

CAMRIS International LLC offers competitive salaries and comprehensive benefits. Please submit your resume online at . CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, interaction, interactionual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law. Some positions or sites may require that the incumbent be fully vaccinated against COVID-19.

Proof of vaccination may be required. Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check.

Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.

POPULAR
Expert AI/ML Applied Scientist - Generative AI and Structured Data
1
Expert AI/ML Applied Scientist - Generative AI and Structured Data
Sunnyvale, CA
Dec 16, 2023

a highly collaborative, caring team environment with a strong focus on learning and development, recognition for your individual contributions, and a variety of benefit options for you to choose from. Apply now! Summary: At SAP, we integrate AI technology with extensive industry-specific data and deep process knowledge to create innovative AI capabilities for all SAP applications.

Large Language Models (LLMs) hold immense potential to change the way we work and develop products. They are reshaping the landscape of Machine Learning across various domains. However, their limited ability to leverage tabular data leaves a considerable share of enterprise data untapped. It is SAP's mission

to overcome this challenge within the realm of Business AI. Our goal is to adapt Foundation Models to SAP data, enabling our clients to solve their business processes more effectively.

Meet your team: SAP's AI organization is dedicated to seamlessly infusing AI into all enterprise applications, enabling customers, partners, and developers to enhance business processes and generate remarkable business value. Join our international AI team where innovation thrives, opportunities for personal development abound, and exceptional colleagues collaborate globally. The Role: Unique opportunity to lead the development of a Foundation Model on structured business data embedded in a diverse business

context. Technical lead for the project team of AI Scientists and Data Engineers, providing strategic guidance and overseeing project execution.

Design a representation suitable for Self-Supervised Learning on data across the entire SAP application and process portfolio. Define processes, methods, hypothesis, experiments and review results from the ground up with an understanding to put them together for End-to-End Foundational Model. Collaborate cross-functionally with other teams to understand needs and requirements, ensuring the Foundation Model aligns with strategic company objectives of embedding AI into our product portfolio. Maintain up-to-date knowledge of AI and Data Engineering trends and apply this expertise to improve team performance and product quality.

Establish and drive research collaborations with academic and commercial partners. Contribute to thought leadership in a revolutionary new data modality for Foundation Models and Generative AI. What you bring: Ph D or master’s degree in Computer Science, Artificial Intelligence, or other relevant disciplines. Extensive experience with Foundation Models as well as Machine Learning Professional experience with Machine Learning on structured data such as in the ERP or CRM domain is preferred.

Deep understanding of issues and opportunities of applying Generative AI in a business context. Proficiency in Python, and experience with ML frameworks such as Py Torch, Tensor Flow, or similar. Exceptional teamwork abilities, strong leadership and strategic thinking skills. Substantial publication record related to LLMs and Foundation Models #SAPAI #SAPAICareers We build breakthroughs together SAP innovations help more than 400,000 customers worldwide work together more efficiently and use business insight more effectively. Originally known for leadership in enterprise resource planning (ERP) software, SAP has evolved to become a market leader in end-to-end business application software and related services for database, analytics, intelligent technologies, and experience management.

As a cloud company with 200 million users and more than 100,000 employees worldwide, we are purpose-driven and future-focused, with a highly collaborative team ethic and commitment to personal development. Whether connecting global industries, people, or platforms, we help ensure every challenge gets the solution it deserves. At SAP, we build breakthroughs, together. We win with inclusion SAP’s culture of inclusion, focus on health and well-being, and flexible working models help ensure that everyone – regardless of background – feels included and can run at their best.

At SAP, we believe we are made stronger by the unique capabilities and qualities that each person brings to our company, and we invest in our employees to inspire confidence and help everyone realize their full potential. We ultimately believe in unleashing all talent and creating a better and more equitable world. SAP is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to the values of Equal Employment Opportunity and provide accessibility accommodations to applicants with physical and/or mental disabilities.

If you are interested in applying for employment with SAP and are in need of accommodation or special assistance to navigate our website or to complete your application, please send an e-mail with your request to Recruiting Operations Team: xyz X@. For SAP employees: Only permanent roles are eligible for the SAP Employee Referral Program, according to the eligibility rules set in the SAP Referral Policy. Specific conditions may apply for roles in Vocational Training.

EOE AA M/F/Vet/Disability Qualified applicants will receive consideration for employment without regard to their age, race, religion, national origin, ethnicity, age, gender (including pregnancy, childbirth, et al), interactionual orientation, gender identity or expression, protected veteran status, or disability. Compensation Range Transparency : SAP believes the value of pay transparency contributes towards an honest and supportive culture and is a significant step toward demonstrating SAP’s commitment to pay equity. SAP provides the annualized compensation range inclusive of base salary and variable incentive target for the career level applicable to the posted role.

The targeted combined range for this position is 177,900 - 392,100 USD. The actual amount to be offered to the successful candidate will be within that range, dependent upon the key aspects of each case which may include education, skills, experience, scope of the role, location, etc. as determined through the selection process. Any SAP variable incentive includes a targeted dollar amount and any actual payout amount is dependent on company and personal performance. Please reference this link for a summary of SAP benefits and eligibility requirements: SAP North America Benefits.

Requisition ID: 378787 Work Area: Software-Design and Development Expected Travel: 0 - 10% Career Status: Professional Employment Type: Regular Full Time Additional Locations: #LI-Hybrid

POPULAR
Scientist - Development - Experimental Cellular Therapeutics Lab
1
Scientist - Development - Experimental Cellular Therapeutics Lab
Memphis, TN
Dec 16, 2023

scale-up in one or more of the following areas: gene therapy vectors, Monoclonal Antibodies, small molecules (i. e. peptides, cytokines), recombinant proteins, or bacterial/viral/DNA vaccines. The position is responsible for the proper conduct of specific projects, collection and analysis of data.

Check out the Experimental Cellular Therapeutics Laboratory (ECTL) here. The job responsibilities include but are not limited to: -Lead the development of manufacturing processes that meet c GMP requirements for cellular therapeutic products: Develops product characterization assays. Gains and routinely updates knowledge related to projects. Maintains proficiency in required laboratory skills

and actively pursue training in new laboratory skills or techniques. Develops or adopts new technologies as needed. -Manufactures cellular therapeutics under c GMP regulations: Effectively collaborates with Human Application Lab, Children's GMP, Clinical team, Quality Assurance and Vector Lab to manufacture cellular therapeutics for clinical trials.

Learns and applies c GMP requirements for manufacturing cellular therapeutics. Follows standard operating procedures, batch manufacturing records, and other relevant documents. Works with extreme attention to detail in a highly regulated environment. -Works with Quality Assurance to ensure compliance of all production activities with: c GMP

regulations Code of Federal Regulations Title 21(21 CFR) part 210 and 211 Current good tissue practice (c GTP) regulations (21 CFR part 1271) EMA (European Medicines Agency) ICH (The International Council for Harmonization of Technical Requirements for medicals for Human Use) Foundation for the Accreditation of Cellular Therapies (FACT) -Maintains accurate and detailed documentation: Maintains electronic laboratory notebook and paper notebook system to document all laboratory activities.

Always keeps accurate dated records. Reports deviations to procedure promptly. -Trains personnel in procedures and techniques of the laboratory: Facilitates orientation of new personnel to the laboratory.

Instruct new staff on use of laboratory equipment. Demonstrates specific standard operating procedures as required. Participates in continuing education. Stays abreast of current techniques by attending seminars, reading articles, attending training sessions and meetings. Exhibits proper knowledge and execution of safety procedures. -Clearly communicates with stakeholders and represents ECTL to present results in various formats and occasions. -Maintains regular and predictable attendance and requires occasional weekend hours as needed. -Performs other related duties as assigned in order to meet the goals of the department and institution.

Minimum Education and/or Training: Bachelor's Degree Required in relevant scientific area. Master's Degree/Ph D Preferred. Minimum Experience: Minimum Requirement: Bachelor's degree with 7+ years experience in relevant scientific area (e. g. GMP: chemistry, biology, chemical engineering, analytical chemistry, biotechnology; ECTL: cellular biology, molecular biology, immunology, biochemistry). Experience exception: 5+ years of experience in relevant area with Master's Experience exception: 3+ years of experience in relevant area with Ph D Prior experience in relevant area to own domain (e.

g. upstream/downstream c GMP experience, process development, HPLC/biological assays) strongly preferred. Experience in lab and scientific project coordination, maintenance, and other research support activities preferred. St Jude Employees receive: Excellent healthcare plans with zero to low health premium costs Onsite health clinic, shop, and exercise facilities Paid parental leave and adoption assistance Immigration Services Tuition Reimbursement St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion.

Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St.

Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. Other Information St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St.

Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

POPULAR
Senior Scientist, In vivo Pharmacology: Immuno-Oncology Early Discovery
1
Senior Scientist, In vivo Pharmacology: Immuno-Oncology Early Discovery
Waltham, MA
Dec 16, 2023

our team in Waltham, MA USA. As a Senior Scientist in the IO Discovery group, you will be a key member of a team focused on delivering all aspects of in vivo pharmacology support. You will bring your theoretical and practical expertise to establish and support mouse models, assay systems and deliver datasets that will have direct impact on the drug discovery process and pipeline.

Accountabilities: In this laboratory-based position within Oncology Research, you will develop, design, conduct and analyze both in vivo experiments to backss the function of our candidate oncology drugs and dissect the mechanism of action of novel cancer therapeutics. You will be expected to support cross-functional

teams and work collaboratively with project leaders to ensure the timely generation, and dissemination of critical program data, and contribute to scientific publication goals.

Essential Skills/Experience: B. S with 5-10, M. S or Ph. D. with 2-5 years research experience in Cancer biology, Immunology or other related scientific subject area. Biotechnology or medical industry experience preferred but not essential. Experience developing and working with complex in vivo models. Experience delivering in vivo pharmacology studies in mouse tumor models. Experience with a range of in vitro skills. Works independently, backsses, and reports data in a clear and concise manner. Maintains a well-developed

understanding of approaches to drug discovery. Ability to drive, manage, execute and deliver results for complex multi-functional projects.

Proven ability to manage, motivate, and develop direct reports. Strong interpersonal and collaboration skills. Excellent communication and presentation skills. A proven track record of high productivity and scientific publications in peer reviewed journals. Desirable Skills/Experience: Experience with xenograft and humanized models of cancer. Experience conducting in vivo research using biologics including, peptides, antibodies, antibody-drug conjugates, engagers and small molecules. Experience designing, conducting and analyzing high parameter flow cytometry immune-phenotyping studies.

Experience in drug development in medical or biotech industries. Experience in leading part of a project through key milestones with tight timelines. At Astra Zeneca's Oncology R&D department, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next.

We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. It's science with an impact-making a difference for patients and people around the world. About the Waltham Site Our Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park Bio Hub, just west of the city center. Our Bio Hub facility, is a bold new R&D initiative, which fosters life science discoveries and the exchange of ideas.

Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers. Our Waltham site offers a variety of amenities to help book productivity and help keep our employees happy and engaged.

This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams and the greater research community. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life. So, if you're curious about what science can do, then you're our kind of person. Join us and help make a difference in the world!

Please contact Bobbi Poole, our Talent Acquisition Partner. Closing Date: January 5, 2024 Competitive remuneration and benefits apply We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package. Where can I find out more- Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Astra Zeneca embraces diversity and equality of opportunity.

We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Please contact us to request accommodation. Date Posted 08-Dec-2023 Closing Date 04-Jan-2024Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be.

We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e. g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

POPULAR
Scientist, In vivo Pharmacology: Immuno-Oncology Early Discovery
1
Scientist, In vivo Pharmacology: Immuno-Oncology Early Discovery
Waltham, MA
Dec 16, 2023

be a key member of a team focused on delivering all aspects of in vivo pharmacology support. You will bring your theoretical and practical expertise to establish assay systems and deliver datasets that will have a direct impact on the drug discovery process and pipeline.

Accountabilities: In this laboratory-based position within Oncology Research, you will develop, design, conduct and analyze in vivo experiments to backss the function of our candidate oncology drugs and dissect the mechanism of action of novel cancer therapeutics. You will be expected to support cross-functional teams and work collaboratively with project leaders to ensure the timely generation and dissemination of critical

program data and contribute to scientific publication goals. Essential Skills/Experience: B. S, in Biology, Pharmacology or other related scientific discipline with 3-6 yrs.

relevant scientific experience; M. S. - 1-3 yrs. MS desired but not required. Experience developing and working with complex in vivo models of cancer. Experience delivering in vivo pharmacology studies in mouse tumor models. Experience with a range of in vitro skills, e. g. cell culture, molecular biology, immunoblotting, flow cytometry and ELISA. Works independently, backsses and reports data in a clear and concise manner. Maintains a well-developed understanding of approaches to drug discovery. Strong interpersonal

and collaboration skills together with evidence of delivery in a team-oriented, collaborative environment.

Excellent communication and presentation skills. Desirable Skills/Experience: Biotechnology or medical industry experience preferred but not essential. Experience with orthotopic xenograft and humanized models of cancer. Experience using biologics including, peptides, antibodies, or antibody-drug conjugates. Knowledge of the medical industry drug discovery process. At Astra Zeneca's Oncology R&D department, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death.

With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our commitment to patients and pioneering spirit are truly embedded and it's what makes our pipeline unique. About the Waltham Site Our Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park Bio Hub, just west of the city center.

Our Bio Hub facility, is a bold new R&D initiative, which fosters life science discoveries and the exchange of ideas. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers.

Our Waltham site offers a variety of amenities to help book productivity and help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams and the greater research community. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life.

So, if you're curious about what science can do, then you're our kind of person. Join us and help make a difference in the world! Please contact Bobbi Poole, our Talent Acquisition Partner. Closing Date: January 5, 2024 Competitive remuneration and benefits apply We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package. Where can I find out more- Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/?

hl=en Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.

We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

POPULAR
Associate Scientist, m RNA Vaccines and Tech
1
Associate Scientist, m RNA Vaccines and Tech
Alabaster, AL
Dec 16, 2023

production and characterization, including but not limited to: standard molecular biology techniques, in-vitro m RNA transcription, capping and in-vitro characterization using cell-free/cell-based assays, with the aim of optimizing vaccine design strategies.

The successful candidate will be part of a very collaborative team and should possess a strong work ethic, be dependable and adaptable to fast-paced environments. What You Will Achieve Perform standard DNA Molecular Biology techniques; Synthesize and characterize m RNA constructs using a variety of assays. Perform cell-based assays to evaluate m RNA vaccine candidates. In collaboration with manager, interpret and summarize experimental

data. Present experimental results at group meetings as needed. Generate and characterize reagents used to perform necessary assays and support maintenance of laboratory supplies.

Maintain laboratory notebooks in compliance with the Pfizer Laboratory Notebook Policy. Performs other duties as assigned. Satisfactorily completes all safety and quality training in conformance with Departmental requirements. How You Will Achieve It Perform standard DNA Molecular Biology techniques; Synthesize and characterize m RNA constructs using a variety of assays Perform cell-based assays to evaluate m RNA vaccine candidates In collaboration with manager, interpret and summarize experimental data. Present

experimental results at group meetings as needed.

Generate and characterize reagents used to perform necessary assays and support maintenance of laboratory supplies. Maintain laboratory notebooks in compliance with the Pfizer Laboratory Notebook Policy. Performs other duties as assigned. Satisfactorily completes all safety and quality training in conformance with Departmental requirements. Qualifications Must-Have B. S Degree in Molecular Biology, Cell Biology, Virology, or a related scientific field with 1-3 years of laboratory research experience. Laboratory hands-on experience with standard molecular biology techniques (eg. PCR, q PCR, cloning, DNA/RNA production and purification, sequencing, etc.

) Working knowledge of molecular biology and sequence analysis software, and proficiency with word processing, Microsoft Office, Graphpad and Geneious. Must be detail oriented; possess problem solving skills, and the ability to handle multiple tasks. Must possess good interpersonal and communication skills and be a team player in a cross-functional collaborative environment. Nice-to-Have Industry experience preferred. Previous experience handling and manipulating m RNA highly desirable. Experience with cell culture techniques, flow cytometry and image-based analysis preferred.

PHYSICAL/MENTAL REQUIREMENTS Basic laboratory training in aseptic technique is essential. The capacity to work effectively in a highly visible research program with time-constrained milestones. Other Job details Relocation support available Work Location Assignment: On Premise The annual base salary for this position ranges from $53,100.00 to $88,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments.

Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U. S. Benefits (uscandidates. ). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, interaction, interactionual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. Research and Development

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Principal Scientist, m RNA Vaccines & Technology
1
Principal Scientist, m RNA Vaccines & Technology
Alabaster, AL
Dec 16, 2023

lipid nanoparticle drug products and participate in the development of next-generation RNA vaccine prototypes. ROLE RESPONSIBILITIES Lead the multi-step design, planning and execution of experiments to characterize the RNAs and their formulations for in vitro studies Develop, establish, and execute novel technology platforms (multi-cellular engineered culture systems, 3D bioprinting platform, high throughput live imaging system) to monitor vaccine-mediated immune responses, including T cell, Treg, NK cell or PBMC based immunotherapy assays Partner with director to contribute to scientific discussions and strategic internal/external collaborations aimed at advancing the RNA Platform Mentor junior

scientists' research activities and provide technical guidance when necessary BASIC QUALIFICATIONS Strong foundation in drug discovery process accumulated in prophylactic and therapeutic vaccine development Comprehensive knowledge and hands on experience with ex vivo cell-based assays to monitor vaccine-mediated T cell immunogenicity Hands on experience with cell culture (primary immune cells and established cell lines) and the utilization of cell-based assays to characterize RNA-based products (e.

g. Multicolor flow cytometry, ELISA/MSD/ELLA, Taqman RT-q PCR, Luminescence, and single cell RNAseq) Strategic agility, strong critical and logical thinking with ability to analyze problems

Contribute creatively to seed innovation projects through literature review and shape execution tactics.

Recommend changes to project direction based on an understanding of current literature and in-house experimental data. Excellent interpersonal, organizational, and collaborative skills, attentive to detail, and the ability to work independently and effectively in a highly dynamic cross-functional matrix and fast-paced environment Ph D in biology, biochemistry, immunology, molecular cell biology or a related field 3+ years relevant industry experience in pre-clinical research and in vaccine technical development PREFERRED QUALIFICATIONS Experience in establishing in vivo/ex vivo models for vaccine development RNA secondary structure and RNA folding characterization and m RNA stability analysis Analysis of m RNA translation through polysome profiling and/or ribosome profiling Data analysis of NGS-based technologies (RNA-seq, Ch IP-seq, sc RNA-Seq, Long-Read sequencing, etc.

) are preferred Experience with managing a small team PHYSICAL/MENTAL REQUIREMENTS Strong abilities in scientific analysis, cross-functional collaboration, people management, scientific writing, and public speaking required NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS On-site (laboratory-based).

Must be able to access or utilize reliable transportation to the Pearl River site Experimental designs may occasionally necessitate being on-site early/late or on weekends as needed Potential to work with/come in contact with infectious materials Work Location Assignment: On Premise The annual base salary for this position ranges from $96,900.00 to $161,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program.

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U. S. Benefits (uscandidates. ). Pfizer compensation structures and benefit packages are aligned based on the location of hire.

The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure.

Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, interaction, interactionual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. Research and Development

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Scientist, Immuno-Oncology
1
Scientist, Immuno-Oncology
Alabaster, AL
Dec 16, 2023

immune-oncology research, and contribute to every stage of pre-clinical drug discovery and development. The preferred candidate should have extensive experience both in vitro and in vivo, including cell biology techniques such as culturing and/or engineering primary tissue cells and cell lines, in vivo techniques such as handling, dosing, dissecting and tissue harvesting of small experimental animals.

As a Scientist, a typical day may include: Performing subcutaneous and liver engraftment experiments: engraftment of primary tissue cells or cancer cell lines into host animals, pre- and post- engraftment care and monitoring, drug administration and tissue harvesting. Animal husbandry, taking

care of experimental animal cohorts. Harvesting tissues of tumors and relevant organs from experimental animals and performing molecular and cellular analysis.

Culturing/maintenance of cell lines and running cell-based assays Analyze and document data, communicate results clearly and concisely to supervisor and peers. Daily lab maintenance (i. e. ordering reagents and supplies) This role might be for you if: You are detail oriented and love both bench work and animal experiments. You are excited to work in a fast-spacing and collaborating research team. You have good time management as well as data documentation and organization skills. To be considered for this opportunity you must possess

a bachelor's of master's degree with a minimum of ten plus year of experience.

Previous experience must include both in vitro and in vivo experiences. The ideal candidates are required to have solid background in molecular biology and cell biology. Solid understanding in small animal surgery and/or flow-cytometry is highly desired. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), interaction, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, interactionual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations.

We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need. The salary ranges provided are shown in accordance with U. S. law and apply to U. S. based positions, where the hired candidate will be located in the U. S. If you are outside the U. S, please speak with your recruiter about salaries and benefits in your location. Salary Range (annually) $90,700.00 - $148,100.00

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Principal Scientist, Cancer Vaccines Research
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Principal Scientist, Cancer Vaccines Research
Cambridge, OH
Dec 16, 2023

immune cell functional assay development, clinical sample analysis, and single cell sequencing. Prior management experience is essential as the successful candidate will be expected to lead a team of scientists and research associates. Here's What You'll Do: Lead and execute research projects in the field of T cell biology, with a focus on cancer vaccine research.

Work with Research and Development teams to design and develop translational assays to evaluate patient responses to cancer therapies. Oversee the development and execution of high-parameter flow cytometry and single cell sequencing technologies to backss primary human T cell activities Interpret and present data in a clear

and concise manner to various stakeholders. Collaborate cross-functionally with other teams to drive project goals. Keep up-to-date with the latest scientific advancements in the field of antigen-specific T cell biology and cancer vaccine research.

Contribute to the development of patent applications. Mentor and manage a team of junior scientists and research associates. Here's What You'll Bring to the Table: Ph D in Immunology, Immuno-oncology, Cancer Biology or a related field. Minimum of 5 years of post-doctoral experience in T cell biology. Minimum of 3 years of industry experience. Extensive experience with high-parameter flow cytometry is required. Proven expertise in developing

primary human immune cell assays. Hands-on experience with single cell sequencing techniques.

Strong publication record in the field of T cell biology and cancer vaccine research. Prior management experience, preferably leading a team of scientists. Excellent communication, leadership, and team management skills. Ability to work in a fast-paced and dynamic environment. This position offers a unique opportunity to contribute to breakthrough research in T cell biology and cancer vaccine research. We provide a stimulating work environment and ample opportunities for career growth. If you are passionate about making a difference in the field of cancer research and ultimately in helping create and develop novel medicines to positively impact cancer patients, we would love to hear from you.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including: Highly competitive and inclusive medical, dental and vision coverage options Flexible Spending Accounts for medical expenses and dependent care expenses Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities Family care benefits, including subsidized back-up care options and on-demand tutoring Free premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipment Adoption and family-planning benefits Dedicated care coordination support for our LGBTQ+ community Generous paid time off, including: • Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafter Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning tools Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options Complimentary concierge service including home services research, travel booking, and entertainment requests Free parking or subsidized commuter passes Location-specific perks and extras!

About Moderna Since our founding in 2010, we have aspired to build the leading m RNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture.

Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U. S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit /careers to learn more about our current opportunities. Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is proud to be an equal opportunity workplace and is an affirmative action employer. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, interaction, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, interactionual orientation, marital or familial status, or any other personal characteristic protected under applicable law.

Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at xyz X@. (EEO/AAP Employer) #LI-MBB1

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Scientist, m RNA Vaccines & Technology
1
Scientist, m RNA Vaccines & Technology
Alabaster, AL
Dec 16, 2023

and lipid nanoparticle drug products and participate in the development of next-generation RNA vaccine prototypes. How You Will Achieve It Build and optimize an optical platform to characterize the RNAs and their formulations for in vitro studies Develop, establish, and execute single molecule approaches to investigate patterns of intra-cellular trafficking and localization of RNA including organelle retention of RNA and spatial RNA polarization, and their impact on translation in mammalian primary cells and established cell lines Develop novel tools to visualize and quantify exogenous m RNA and protein interactions in subcellular compartments and in RNA granules with high spatiotemporal resolution,

at the single molecule level QUALIFICATIONS Must Have's Strong foundation in RNA Cell biology MS in biology, biochemistry, immunology, molecular cell biology or a related field with 4+ years of relevant industry experience in pre-clinical research and in vaccine technical development OR Bachelor's degree in biology, biochemistry, immunology, molecular cell biology or a related field with 6+ years of relevant industry experience in pre-clinical research and vaccine technical development Comprehensive knowledge and hands on experience with confocal microscopy-based single molecule Fluorescence In Situ Hybridization (sm FISH) and Immunofluorescence assays including Cell Painting and Fluorescent

Recovery After Photobleaching (FRAP) assay.

Proficiency in High-Content Imaging using differential interphase contrast, epifluorescent, confocal laser scanning, spinning disc confocal, total internal reflection fluorescence, multi-photon microscopies and associated imaging software. Hands on experience with cell culture (primary immune cells and established cell lines) and the utilization of cell-based assays to characterize RNA-based products (e. g. Multicolor flow cytometry, ELISA/MSD/ELLA, Taqman RT-q PCR, Luminescence, Single cell RNAseq) Experience with standard molecular biology techniques: RT-q PCR, molecular cloning, aseptic technique, cell culture, DNA/RNA isolation, DNA/RNA transfection Excellent computer proficiency (MS-Word, Excel, Power Point; Graph Pad & Flow Jo; molecular biology tools and software applications, including Genewiz, Geneious, Twist, etc.

) Excellent interpersonal, organizational, and collaborative skills, attentive to detail, and the ability to work independently and effectively in a highly dynamic cross-functional matrix and fast-paced environment. Nice to Have Technical proficiency with imaging analysis software (Image J, Metamorph, Imaris) Ph D Degree in biology, biochemistry, immunology, molecular cell biology or a related field Proficiency in process development & automation solutions Experience in Ribosome/polysome profiling, RNA-RNA and RNA-Protein interactions and target identification using NGS.

Practice designing and running experiments independently. PHYSICAL/MENTAL REQUIREMENTS Strong abilities in scientific analysis, cross-functional collaboration, scientific writing, and public speaking required. Standard laboratory conditions - sitting, standing, primarily lab-based. Ability to interpret, analyze, and present complex data to colleagues. Math skills for basic laboratory calculations: dilutions, molar ratios, etc NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS On-site (laboratory-based).

Must be able to access or utilize reliable transportation to the Pearl River site. Experimental designs may occasionally necessitate being on-site early/late or on weekends as needed. Potential to work with/come in contact with infectious materials. Other Job Details Relocation support available. Work Location Assignment: On Premise The annual base salary for this position ranges from $72,700.00 to $121,200.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary.

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U. S. Benefits (uscandidates.

). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure.

Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.

If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, interaction, interactionual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.

Pfizer is an E-Verify employer. Research and Development

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Sr. Scientist - Bioassay Screening - Biotherapeutic Drug Discovery
1
Sr. Scientist - Bioassay Screening - Biotherapeutic Drug Discovery
Alabaster, AL
Dec 16, 2023

communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Lilly's Biotechnology Discovery Research Organization in San Diego is dedicated to discovery and development of biotherapeutics spanning a wide range of therapeutic areas.

Our commitment to innovation drives continuous improvement in patient outcomes through drug discovery, engineering, and characterization while leveraging cutting-edge automation to bolster many of these workflows. At the helm are an accomplished team of scientists and engineers that spearhead initiatives that bring

us closer to the next life-saving breakthrough. It's an exciting time to join Team Lilly! Responsibilities: As a member of the Lilly Biologics Screening Group and Automation Team, the focus of the successful candidate will be to support research teams across multiple therapeutic areas by miniaturizing, adapting and executing assays to screen biologics using state-of-the-art lab automation.

The successful candidate will thrive in a fast-paced, highly collaborative environment in which they work synergistically and creatively with local colleagues and multiple project teams across the organization. Key Objectives/Deliverables: The candidate will interface with multiple project teams across

the organization and outside Lilly to adapt bioassays to mid-high throughput automated formats (96W/384W), validate and execute screens, and identify hits for biologics discovery efforts using state-of-the-art automation platforms.

They will also develop de novo cell-based assays as needed. The candid will apply specialized commercial and internal software tools to perform detailed analysis of biological activity, statistical evaluation of assay performance and generate comprehensive data reports. The successful candidate will work with automation engineers to create, troubleshoot, and validate automated methods on liquid handling systems and workstations. The successful candidate will engage in the identification and evaluation of novel procedures or technologies that could serve to bolster the productivity of the antibody discovery and protein engineering teams or help in development of new capabilities for the screening group The candidate will clearly present results to collaborators, participate in project team meetings and present at internal forums The candidate will maintain clear, organized data, SOPs, and electronic notebook entries with great attention to detail Basic Qualifications: B.

S or M. S. in biology, biotechnology, biochemistry, molecular biology, or a related field with 3+ years relevant research experience in assay development & execution, preferably in drug discovery Additional Skills and Preferences: Proficient in assay development, optimization and troubleshooting of plate-based bioassays in 96/384W formats.

Demonstrated expertise in diverse assay methods and technologies, such as reporter bioassays, ELISA, FRET/BRET, Alpha-ELISA and co-culture assays Solid skills in cell culture techniques required with working knowledge of cellular signaling Experience working on an automated platform in a screening group is preferred.

Demonstrated ability to use multiple software platforms for plotting and statistical analysis of large experimental data sets (e. g. TIBCO Spotfire, Graphpad Prism, Genedata Screener) is preferred. Demonstrated ability to successfully take on challenges and quickly adapt to new responsibilities. Detail-oriented and highly organized with the ability to run and prioritize multiple projects to meet timelines Excellent written and oral communication skills, with a demonstrated ability to work in a highly collaborative team environment. Highly motivated with ability to work and think independently, research the literature, and master new skills, methods and technologies that enhance departmental capabilities highly preferred.

Additional Information: Location: San Diego, California Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively " Lilly" ) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( xyz X@lists. ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process.

Any other correspondence will not receive a response. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, interactionual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles.

Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups. #We Are Lilly

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Scientist, Cell Therapy
1
Scientist, Cell Therapy
Alabaster, AL
Dec 16, 2023

inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow n Research & Development, LLC is part of the Janssen medical Companies.

Janssen Research & Development, L. L. C. a division of Johnson & Johnson's Family of Companies, is committed to building upon the clinical success of autologous, CAR-directed cellular therapies to benefit more cancer patients. The Immuno-Oncology, Cell Therapy research team is dedicated to research that improves the accessibility and therapeutic potency of cellular therapies to address unmet medical needs and achieve safe and durable

responses. Ultimately, we aspire to provide curative treatment options for cancer patients. Currently, our team is working to develop the next generation of off-the-shelf therapies that incorporate advancements in i PSC technology, genetic engineering, allogeneic biology, and optimized chimeric antigen receptor design.

We are seeking an experienced, highly motivated, and creative scientist to join us in our mission to improve next generation of cell therapy products for cancer patients. Candidates with a strong immunology background and experience working with CAR T cells are preferred. In this role, the candidate will be expected to lead discovery programs and effectively collaborate

with colleagues in other functional areas. They will be responsible for developing innovative mechanisms to improve CAR T cell therapy.

Success in this position will require a positive, can-do attitude, the ability to work well within a cross-functional team, and the ability to design and implement critical assays to study human CAR T cell biology. The role is based at our research campus in Spring House, Pennsylvania. The Scientist will: Lead discovery research team to build deep understanding of novel cell therapy products and recommendations for next generation platform Design, implement, analyze, and interpret in vitro and in vivo assays to interrogate CAR T cell therapy performance Innovate and improve current methodologies to improve therapeutic activity of cell therapy products Collaborate effectively with internal and external colleagues to get critical feedback and advance key findings Distill complex ideas into practical next steps Communicate results in writing and oral presentations to enable key decisions Keep accurate and timely records of all experiments Mentor a team of associates and scientists, and promote professional development Ph D degree with post-doctoral and/or industry experience in immunology or a related discipline is highly preferred.

In place of a Ph D, a minimum of 12 years of experience performing progressively advanced duties beyond a B. S. degree, OR at least 3 years of experience performing progressively advanced duties at the Senior Associate Scientist level, or the equivalent training/experience is required. Strong foundation in immunology with deep understanding of T cell biology, signaling and effector differentiation is preferred Hands-on experience working with human primary T cells and CAR T cells is preferred Ability to design, perform and interpret in vitro and in vivo CAR-directed cell therapy experiments to backss cytotoxicity, cytokine production, cell proliferation is strongly preferred Applied experience with multiparameter flow cytometry design and analysis is strongly preferred Ability to work independently, and manage multiple projects and workstreams simultaneously Ability to contribute to various projects outside of their own, and collaborate with team members from all relevant functions Ability to keep up-to-date with the literature and be a thought leader in cell therapy Ability to mentor and develop Ph.

D. and non-Ph. D. scientists Ability to stay organized, pay attention to details, plan for complicated long-term projects, and maintain detailed records Demonstrate clear and professional verbal and written communication Johnson & Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, interaction, interactionual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.