Scientist level, with backgrounds within Oncology and Immuno-Oncology. We are seeking someone to independently oversee the development and execution of biomarker strategies across one (or more) therapeutic areas depending on their areas of expertise. As a Senior Principal Scientist, a typical day may include the following: - Program-level PM lead for implementation of strategic vision for clinical biomarkers in Oncology / Immuno-Oncology development that will broadly enable advances in target identification, indication selection, early indication of biological activity and patient stratification/selection- Serve as an individual contributor and senior-level representative of Precision Medicine
on Oncology development teams and deliver biomarker strategies to key programs from initial concept to execution, data delivery and results interpretation- Collaborate with Oncology Discovery Research and product development teams to facilitate appropriate incorporation of Precision Medicine and clinical biomarker strategies for molecules in discovery phases (leading to candidate molecule selection)- Represent Regeneron and work with colleagues from allied companies to develop and implement strategies for partnered alliances- Collaborate with clinical operations teams to implement specific biomarker and exploratory sample collection and analyses in Oncology clinical studies in selected programs-
Design, oversee and manage internal and external research collaborations in areas of clinical technologies and translational research- Accountability for ensuring complex clinical assays used in programs in the TFA portfolio of Oncology clinical development are fit-for-purpose (whether developed and validated internally or externally)- Collaborate with internal Regeneron laboratories (e.
g. Discovery Research, Molecular Profiling, Regeneron Genetics Center, DNA core, Bio Analysis, etc. ) to develop plan for validation and application of research assays This role may be for you if: - You have the ability to drive, manage, execute and deliver results for complex multi-functional projects- You have excellent communication and presentation skills and high emotional intelligence, organizational skills and effective team skills- Strong track record in mentorship and development of direct reports To be considered for this position, you must have a Ph.
D. and/or M. D. and 5+ years' experience participating effectively on cross-disciplinary teams in medical or biotech industry. Additionally, at least 2-3 years in clinical development, with a track record of high impact in drug development. Other levels considered depending on experience. We are need experience in Oncology, Immuno-Oncology or Immune-Inflammatory disease drug development.
Extensive insight and experience in basic, translational or clinical research related to biomarkers, pharmacogenetics, imaging, and/or other clinical technologies. We need someone with strong understanding of technical, regulatory, clinical, and strategic aspects of these areas required. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), interaction, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, interactionual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations.
We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need. The salary ranges provided are shown in accordance with U. S. law and apply to U. S. based positions, where the hired candidate will be located in the U. S. If you are outside the U. S, please speak with your recruiter about salaries and benefits in your location. Salary Range (annually) $145,400.00 - $237,200.00
code and system deficiencies, and preparing accurate and timely inspection reports. Essential Duties & Responsibilities: Install or upgrade suppression systems in commercial and residential buildings Test and repair systems already in place Perform inspections to ensure suppression systems are installed according to code Complete detailed inspection reports, documenting any issues Protect and maintain company equipment Inspect and maintain the truck and all related equipment, putting in repair requests as necessary to maintain safe operation Respond to emergency service calls Perform other duties assigned by management Education/Qualification: Experience with commercial and residential Kitchen
Hood Suppression Systems Must have good interpersonal skills and be able to work in a team environment as well as work independently Must have a clean driving record and reliable transportation to/from the office or job site Founded in 1984 by Alan Hartline, The Hartline Company helps businesses protect people and property through security monitoring, CCTV and access control in addition to fire sprinklers, fire alarms, extinguishers, emergency lighting, suppression and kitchen hood systems.
Based in Lake Wales, Florida, and serving customers throughout Lakeland, Tampa and Orlando, Hartline's end-to-end offerings include testing, inspection, maintenance and installation of high-quality
life safety systems. Acquired in March 2023 Hartline is now a Pye-Barker company.
Since 1946, Pye-Barker Fire & Safety has been protecting communities through fire suppression and security alarm services. Pye-Barker Fire & Safety is a collective of the most prominent and reputable fire and life safety protection companies in the nation. Job Posted by Applicant Pro
transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers. /working-with-us. At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In
oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change.
We bring a human touch to every treatment we pioneer. Join us and make a difference. Position Summary The Principal Scientist, CV Pharmacology will the lead pharmacology initiatives supporting our pipeline in Cardiovascular Drug Discovery. The position requires subject matter expertise in heart disease and the ability to work independently and collaboratively in a team-driven environment. The role involves people management and potential hands-on work in the laboratory,
as needed. The ability to provide input on the in vivo strategy of CV programs is vital to this role.
This position is based in Brisbane, CA. Key Responsibilities Supervise talented scientist staff with expertise in CV pharmacology, predominantly focused on cardiac in vivo physiology. Laboratory leadership via hands-on experimentation and troubleshooting; expert in cardiac mechanics using invasive hemodynamics and echocardiography; experience handling animals for disease heart research. Ensure smooth interactions and appropriate support levels to facilitate drug discovery progression within the working groups. Ensure appropriate interface with translational research and early development teams to ensure pre-clinical pharmacological testing supports molecule progression into the clinic.
Establish and implement a strategy to identify and validate new pharmacological models. Be a contributor to the overall drug discovery strategy development within CV Drug Discovery; past drug target leadership is a plus. Support compliance with institutional animal care and use policies. Day to day responsibilities include team management in the laboratory, data and protocol reviews, presentations to working groups and upper management, training staff in sophisticated CV experimental methods as needed, hands-on laboratory experimentation.
Manage the career progression of CV Pharmacology team, as needed. Write pharmacology reports and regulatory documents to support FDA filings. Contribute to the leadership of the CV Drug Discovery team; policy matters, recruitment initiatives, succession planning, diversity. backss pharmacological suitability of potential business development opportunities, as needed. Basic Qualifications Bachelor's Degree 8+ years of academic and / or industry experience Or Master's Degree 6+ years of academic and / or industry experience Or Ph.
D. or equivalent advanced degree in the Life Sciences 4+ years of academic and / or industry experience Preferred Qualifications & Experience Ph. D. or equivalent advanced degree in the Life Sciences Ph D; 4+ years of academic and / or industry experience. Hands-on role as needed; expertise in cardiac mechanics (hemodynamics and imaging modalities) Expertise in the field of CV Pharmacology with a strong focus on heart failure; understanding of sarcomere biology, physiology and related drug targets is a plus. Prior drug discovery expertise within an industrial setting is highly desirable.
Strong core belief in the care of animals; understanding of animal welfare ethics and policy. Understanding of KO and transgenic model creation. Demonstrated success in interfacing with development teams and team leaders. Demonstrated success in line-managing teams of scientists via direct reporting or dotted line management. Excellent verbal and written communication skills. Commitment to developing one's own leadership skills via participation in scientific management training. The starting compensation for this job is a range from $121,000 - $152,000 plus incentive cash and stock opportunities (based on eligibility).
The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location. Why You Should Apply Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as " Transforming patients' lives through science™ " every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to xyz X@.
Visit careers. /eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
degrader compounds and drive drug discovery efforts for both platform and pipeline projects. You should be able to work independently while contributing to a team environment and manage several projects simultaneously. The successful candidate must stay current with applicable internal/external scientific literature and be able to analyze, document, and report data rigorously.
You should possess excellent communication skills and be proficient in presenting in front of groups. Join our team at Abbvie and contribute to ground-breaking research in the field of target protein degradation. Responsibilities: Independently conceive and execute rigorous scientific research to profile potency,
efficacy, and mechanism of action for degraders (including, but not limited to ternary complex formation and ubiquitination) utilizing plate-based biochemical/cellular assays and quantitative western blot Innovate by developing novel biochemical and cellular assays to support structure-activity relationship (SAR) studies for degraders Drive and contribute to pipeline projects in collaboration with Therapeutic Area and Platform biology leads.
Demonstrate a high level of initiative and proficiency in troubleshooting experiments and be an internal leader by example for high standards in data analysis and quality Maintain good written records of laboratory procedures and communicate research
findings in cross-functional project team meetings and publications.
Qualifications: Position will be filled at level commensurate with extent of education, experience, and accomplishments Scientist II: BS in Biochemistry, Biophysics, Molecular Biology, Cell Biology, or related field of Biological Sciences with typically 7+ years of experience or MS and typically 5+ years of experience Sr Scientist I: BS Biochemistry, Biophysics, Molecular Biology, Cell Biology, or related field of Biological Sciences with typically 10+ years of experience, MS and typically 8+ years of experience, or Ph D and typically 0+ years of experience Demonstrated track record of scientific achievement (publication/presentation record) Proven ability to develop, analyze, and interpret assays for interrogation of biological questions Proficiency in standard biochemical and/or cellular/molecular techniques such as TR-FRET, Alpha LISA, Western Blots, ELISA, and Nano BRET Expertise/background in ubiquitin proteasome system biology or targeted protein degradation preferred, but not required Experience in small molecule drug discovery in academia or industry preferred, but not required Excellent problem-solving and multi-tasking skills in a fast-paced environment Must be a team-player with strong oral and written communication skills Abb Vie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion.
It is Abb Vie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, interaction (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, interactionual orientation, marital status, status as a protected veteran, or any other legally protected group status.
and we believe the best is yet to come. We are looking for a Principal Data Scientist to join the Predictive Analytics team at Hasbro! This team is responsible for analytics in the domains of forecasting, pricing, and media. The data ecosystem is complex, and we are seeking a team member to lead the expansion of our forecasting capabilities for Nerf, Play-doh, Magic the Gathering, Dungeons and Dragons, and other top brands!
The primary directive for this role is to develop forecasting models for toy and game demand that: improve on the accuracy of existing models, incorporate and explain the role of macroeconomic and other covariates, and can supply other forecasting endeavors with useful
inputs and checks. This role will develop and head a center of excellence for forecasting and related methods that specifies best practices, catalogs and curates findings specific to our business, educates workers in the wider business, and stays up to date on the state of the art.
Data Scientists on the team are empowered to build the products the business needs for themselves in our Azure/Databricks ecosystem equipped with turnkey compute resources and cohesive access to the required data sources. They work closely with our supporting Data Engineering team using the same toolset, ensuring that model development and production hardening occur naturally and are supported by all the MLOps
amenities the ecosystem has to offer. This is largely an individual contributor role, but is expected to have 1 or 2 direct reports and will be supported by outsourced engineers or data scientists whose workstreams will need to be managed.
This position can be based in Pawtucket, RI or located remotely in the Eastern Time Zone. A day in the life of a Principal Data Scientist - Forecasting: Authoring model implementations in the Python scientific stack. Specifying prerequisite work for data engineering groups. Procuring additional data sources to support forecasting, or advocating for changes to Hasbro’s data ecosystem that would improve forecasting. Documenting findings on which methods work for Hasbro, what special treatments are necessary, and why.
Researching and specifying mathematical forms for forecasting models. Mentoring and leading a small team, and specifying work for outsourced data science capacity. Visualizing and interpreting model results for key business partners. What you'll bring: Proficiency with Python, SQL, and git including: Python plotting libraries, Pandas, scikit-learn; Py Torch or Tensorflow; A probabilistic programming library like Pyro, Tensorflow Probability, or Py MC. Bonus proficiencies: Python Darts package, dbt, Dash.
Experience modeling hierarchical ensembles of timeseries using global methods. Demonstrated ability to conceive of and author data generating processes to produce simulated datasets for model backssment and development. Guided small teams from start to finish of modeling projects spanning years. Academic research skills: finding relevant papers, manipulating the maths therein, comparing a method’s written and mathematical description with its programmed implementation. Worked with ML Engineers to establish “always on” loops of model training, validation, deployment and inference. Forecasting experience in a complex environment that is highly seasonal or has a high volume of sku's is strongly preferred.
Master’s degree or equivalent in physics, mathematics, or other hard science. Hasbro’s world-class brands and talented people are our greatest assets. One of the ways we invest in you is through a competitive and contemporary benefits package. Your particular benefits package will depend on your position, location, local legal requirements and years with the company. Here’s a look at what your benefits package may include: Medical, Dental & Vision Insurance, Half-day Fridays year round, Paid Vacation Time & Holidays, Generous 401(k) match, Paid Parental Leave, Team Hasbro Volunteer Program, Employee Giving & Matching Gifts Programs, Tuition Reimbursement, Toy Discounts and more!
Hasbro is committed to equality of opportunity in all aspects of employment. We are committed to making all employment decisions without regard to race, color, religion, interaction, interactionual orientation, gender identity or expression, national origin, age, marital status, or any other legally protected status. #LI-GA1 #LI-REMOTE
