with computational biologists, immunologists, and translational biologists in Oncology Research support cancer vaccine discovery, translational research, and clinical development. Here's What You'll Do Identify immunogenomics datasets and tools (such as IEDB, IMGT) and build analytical solutions for oncology target identification and design Using public and proprietary sequencing datasets, design and interpret bioinformatics analysis to derive insights for biological hypothesis and biomarker discovery Stay up to date with current state-of-the-art practices of multi-omics data analysis and interpretation, particularly in the fields of cancer immunogenomics Collaborate closely with computational
and experimental biologists to support oncology research and clinical development Here's What You'll Need (Minimum Qualifications) Ph.
D. in Bioinformatics, Computational Biology, Systems immunology, or related quantitative discipline Minimum 2 years Bioinformatics, Computational Biology, or related experience in industry Experience with -omics data analysis, including RNA-seq, WES, immune repertoire sequencing Strong coding skills with R and/or Python Experience with high performance computing and AWS cloud computing platform Here's What You'll Bring to the Table (Preferred Qualifications) Prior experience leading the development and productization of prediction algorithms, ideally in
the bioinformatics space Strong problem-solving skills and a results-oriented mindset Demonstrated cross-functional collaboration with multidisciplinary teams Curious about exploring a new pathway for drug discovery Be bold in proposing and delivering on creative experimental designs and ideas Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including: Highly competitive and inclusive medical, dental and vision coverage options Flexible Spending Accounts for medical expenses and dependent care expenses Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities Family care benefits, including subsidized back-up care options and on-demand tutoring Free premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipment Adoption and family-planning benefits Dedicated care coordination support for our LGBTQ+ community Generous paid time off, including: • Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafter Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning tools Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options Complimentary concierge service including home services research, travel booking, and entertainment requests Free parking or subsidized commuter passes Location-specific perks and extras!
About Moderna Since our founding in 2010, we have aspired to build the leading m RNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U. S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit /careers to learn more about our current opportunities.
Moderna is a smoke-free, alcohol-free and drug-free work environment. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is proud to be an equal opportunity workplace and is an affirmative action employer. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, interaction, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, interactionual orientation, marital or familial status, or any other personal characteristic protected under applicable law.
Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at xyz X@. (EEO/AAP Employer) #LI-JL2
clinical efficacy to Moderna therapies, and extrapolating from these observations to enable future Moderna therapies. It is our intention to expand the discovery process from pre-clinical studies into the realm of clinical investigation. Reporting to the Executive Director of Clinical and Translational Computational Oncology, the Principal Scientist will be a key member of a high performing team responsible for understanding the clinical mechanisms of Moderna cancer therapies, from cancer vaccines to other types of immune engagers for the treatment of cancer.
You will be an innovative and collaborative computational scientist with knowledge of clinical trials, translational analytics,
skill in the area of mining genomics and understanding of oncogenic and immune-oncological mechanisms with high learning agility. In collaboration with Translational Medicine scientists, you will develop and apply computational methods to analyze large datasets coming from the clinical studies in Moderna's oncology portfolio and publicly and commercially sources datasets.
The candidate must thrive in a fast-paced environment with high expectations. Integrity, ability to share experimental issues and troubleshoot, curiosity, collaborative spirit, respect for people, exemplary work ethic and setting the bar high are key values to thrive in our Team. Here's What You Will Do: Use computational
approaches to analyze complex multimodal internal clinical and publicly available or commercial patient datasets in order to extract clinically actionable insights Analyze complex multi-omics data across various data modalities and connect insights and observations to clinical endpoints Focus on mechanistic questions related to a program in relationship to the broader Moderna oncology portfolio and the landscape of existent oncology therapies.
Work with internal groups at Moderna as well as external partners to solve problems using cutting-edge data visualization and analysis Independently communicate findings to multiple parties and contribute to research publications Collaborate closely with Translational Medicine and Oncology scientists to ensure that data is effectively utilized for high level impact Here's What You'll Bring to the Table: Minimum Qualifications Ph D plus 5 or more years of experience in a quantitative field (i.
e. bioinformatics, computational/systems biology) within industry drug discovery and development setting Strong programming ability in a language such as Python or R Experience analyzing genomics data from clinical trials in an industry setting Experience with the analysis of NGS data Experience with applying machine learning methods (ML/AI) to biological data Preferred Skills Strong grounding in the state-of-the art with respect to single cell biology and computational analysis Ability to quickly conceive and implement custom computational methods and algorithms and apply them to large data sets Experience using computational methods to extract insight from large datasets Experience working on problems involving complex biological systems at high-resolution Creative problem solver who seeks finding useful biologically relevant information in data Experience working in an applied biological field such as immunology, cancer, or immune-oncology Experience with m RNA therapies and LNP delivery technologies Experience with applying machine learning methods (ML/AI) to analyzing clinical images (i.
e. H&E stains) Strong scientific background, including an understanding of molecular biology and NGS techniques Experience working with multiple sequence alignments and large sequence datasets Familiarity with common bioinformatics tools for NGS data analysis Ability to work both independently and collaboratively Proficiency with high performance computing, preferably on public clouds (i. e. AWS, GCP, Azure) Outstanding written and verbal communication skills, ability to work with colleagues from diverse scientific backgrounds and cultures Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including: Highly competitive and inclusive medical, dental and vision coverage options Flexible Spending Accounts for medical expenses and dependent care expenses Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities Family care benefits, including subsidized back-up care options and on-demand tutoring Free premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipment Adoption and family-planning benefits Dedicated care coordination support for our LGBTQ+ community Generous paid time off, including: • Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafter Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning tools Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options Complimentary concierge service including home services research, travel booking, and entertainment requests Free parking or subsidized commuter passes Location-specific perks and extras!
About Moderna Since our founding in 2010, we have aspired to build the leading m RNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture.
Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U. S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit /careers to learn more about our current opportunities. Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is proud to be an equal opportunity workplace and is an affirmative action employer. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, interaction, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, interactionual orientation, marital or familial status, or any other personal characteristic protected under applicable law.
Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at xyz X@. (EEO/AAP Employer) #LI-JL2
the benefit of patients. We have an exciting opportunity to join Sanofi at our Cambridge Crossing research campus as a (senior) distinguished scientific leader working in translational immunology in our type 2 immunology cluster. Focusing on Dupixent, an approved biological medication for several diseases including Atopic Dermatitis and Asthma, your position will direct our research strategy for enhancing our understanding and competitiveness of this exciting therapy.
This translational immunology role will incorporate learnings from research and clinical studies into strategies developed together with our partners in Development, Medical Affairs and Commercial to drive our research directions
and maximize the value of Dupixent. This position will also assume responsibility for scientific leadership of Itepekimab, currently in clinical development for COPD.
Working in a highly matrix environment, this position will involve all aspects of the medical business and require skills aligned with being able to integrate and contribute to decisions in Research, Development, Medical Affairs and Commercial. The incumbent must be a strong communicator and skilled in managing stakeholder relationships. There will also be significant opportunities to develop and contribute to external collaborations with renowned academic institutions and work closely with our partners at Regeneron. We
are searching for someone with a strong knowledge of immunology, particularly Type 2 diseases, and an ability to lead through strategic coordination and collaboration.
The position will lead a team of dedicated scientists and therefore significant managerial and mentorship experience is essential. The incumbent will work independently, pro-actively and serve as an impactful contributor to transverse initiatives to support our business objectives, including maintaining a national and international reputation in the external scientific community through high impact publications, productive scientific collaborations, and active participation in conferences.
This position reports directly to the Type 2 Immunology Cluster Head. Job Responsibilities: Identifies and develops scientific strategies to support research business goals and lead a translational immunology research team to initiate, design, and execute research experiments. Build strong collaborative relationships with our internal and external partners to ensure programmatic activities relevant to our clinical experience and research interests. Work collaboratively with multifunctional teams across Sanofi to leverage resources and ensure our preclinical research efforts are aligned with strategies to support the successful development of Dupixent and Itepekimab.
Identify multidisciplinary solutions and make complex decisions and recommend a course of action to troubleshoot issues. Develop and manage relationships with external academic collaborators Communicate research through peer-reviewed publications and presentations to internal and external audiences Maintain a thorough and up to date knowledge of scientific and medical developments in the field and incorporate into in-house strategies as appropriate. Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials such as controlled drug and radioactive compounds.
Supervise a team several Ph. D. and non-Ph. D. scientists, guide and evaluate the performance of those individuals, and be accountable for the effective performance of the team/individuals. Basic Qualifications: Ph D in Immunology or a related field with 12+ years of related work experience, including successful postdoctoral training and experience. Possesses leading-edge scientific understanding and working knowledge of principles, concepts, and practices in the field of type 2 immunology, including peer-reviewed publications and presentation history in notable scientific journals and forums.
Outstanding track record of scientific publications, presentations, patents, projects as senior author/contributor. Demonstrates continuous growth in depth and breadth of personal scientific knowledge and understanding of strategic goals of group, team, and company Strong managerial and mentorship skills and experience Possesses strong communication and presentation skills and an exceptional work ethic. Acts independently to achieve pre-determined goals and objectives Able to identify multidisciplinary solutions to problems, make complex decisions and recommend a course of action to senior level management Highly motivated, independent, collaborative, and able to communicate effectively with a cross-functional team Exercises foresight and judgement in planning, organizing, and guiding complex projects Fosters a culture of employee growth and development Preferred Qualifications: Direct research and strategic experience in Type 2 immunological diseases Experience with translational medicine, including precision immunology Proven track record in the medical industry.
At Sanofi R&D North America, we deliver meaningful solutions for patients.
We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce - and workplace - which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society. Sanofi Inc. and its U. S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce.
All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; interaction, gender, gender identity or expression; affectional or interactionual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SA #LI-SAAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values.
We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
inspection of safe and effective sterile (injectable) medical products.
Operation of secondary packaging line equipment, labelling, and equipment cleaning. Interacts with Quality, Technical Services, Maintenance, Warehouse Departments, and other departments as required.
Ensures that daily production is carried out according to current SOP's ensuring absolute compliance to quality standards. The Operator is responsible for documenting daily production outputs and efficiencies and keeps other stakeholders involved and informed. Challenges during production are documented and resolved by means of various LEAN tools. Collaborates in the training of colleagues. Key Responsibilities:
Set-up, operation, and troubleshooting of manufacturing equipment: including (but not limited to) Manual Inspection Booths, Semi-Automated Inspection Machine, Secondary Packaging Machines and ancillary equipment (conveyors, pallet jacks, etc.
) within validated parameters and in compliance with c GMP's. Operation of automated equipment through a Human Machine Interface (HMI). Clear and concise written documentation to support GMP activities. Performs line change overs and simple-to-moderate equipment adjustments. Supports the creation and updating of procedures enabling the improvement of quality, compliance, and overall process performance. React to issues on the production line
and start up systematic problem-solving enabling colleagues to support root cause analysis.
Adhere to c GMP's, SOP's, Batch Record processing steps, and site environmental and safety policies. Support a continuous improvement culture and mind set within the department. Possess strong commitment to quality and compliance. Guide colleagues in the importance of proactive behavior regarding improving the work environment towards zero accidents. Work closely together with quality to solve quality issues as they occur and ensure timely release of products. Responsible for execution and completion of individual Training per required curriculum. Ensure processes and products are in compliance with all local, state, and federal rules and regulations.
Oversee that processes are in CGMP compliance, and establish systems that identifies opportunities for improvement and makes constructive suggestions for change to improve process effectiveness to heighten quality. Develop knowledge of and understand regulatory requirements such as 21CFR Parts 210 and 211, c GMP's, FDA, OSHA and other regulatory agencies. Requirements: High School Diploma or GED; Associates Degree in a natural science or technical curriculum preferred Prior experience in a regulated environment; medical or medical device manufacturing experience preferred Must be able to learn and develop a working knowledge of c GMP's; previous knowledge of c GMP requirements preferred Prior experience with complex high speed packaging equipment Experience with quality control technology including vision, robots or automation preferred Ability to clearly read and write English Demonstrates a strong desire to continuously learn and improve Personnel engaged in the manufacture, processing, packing, or holding of a drug product shall wear clean clothing appropriate for the duties they perform.
Protective apparel, such as head, face, hand, and arm coverings, shall be worn as necessary to protect drug products from contamination. Candidate will not be permitted to wear (in the classified manufacturing areas) jewelry, makeup, hair extension, or any exterior adornment (religious articles will be evaluated on a case-by-case basis as to backss impact on controlled environment and drug product). Physical Requirements of the Role: Adequate vision required, must be able to successfully pass visual acuity requirements (20/20 corrected vision, distinguish colors as required. Visual Acuity requirements are tested annually).
Ability to stand, sit, and/or walk for long period of time. Ability to operate material handling equipment. Ability to lift, push, and/or pull up to 50 lbs frequently. Position requires continuous standing and walking. Must be able to be gown qualified. Any person shown at any time (either by medical examination or supervisory observation) to have an apparent illness or open lesions that may affect the safety or quality of a drug product shall be excluded from direct contact with components, drug product containers, closures, in-process materials, and drug products until the condition is corrected or determined by competent medical personnel not to jeopardize the safety or quality of drug products.
All personnel shall be instructed to report to supervisory personnel any health conditions that may have an adverse effect on drug products. #LI-AH1#LI-Onsite Xellia medicals is owned by Novo Holding A/S and is a specialty medical company leading in the development, manufacture and supply of anti-infective treatments. Headquartered in Copenhagen, Denmark, Xellia has global facilities in Europe, North America, and Asia, currently employing over 1700 people.
With over 100 years of industry experience in developing last resort treatments for infectious diseases, Xellia is focused on the supply of products which not only save lives, but also improve and enhance patients' quality of life. Together with us, you can help lead the fight against bacterial infections. Read more about Xellia medicals here
