antibody drugs. Our patented Helicon peptide technology allows us to modulate the activity of well-known intracellular disease drivers that have thus far evaded small molecule and biologic therapies. Fog Pharma's lead program targets ---Catenin, an oncogenic driver in the WNT pathway.
Inhibition of ---Catenin has the potential to benefit 10-15% of all cancer patients, and is just one of many opportunities for Fog's lead-discovery platform to change future medicines, therapies and lives. Our Phase 1 clinical trial has been initiated for this program. What's the opportunity? As a Process Chemist at Fog Pharma, you will partner with scientists across the organization to discover and develop
the best Helicon TM peptides and tailor them to fit patients' needs. We are looking for an enthusiastic and innovative Process Chemist to join a multidisciplinary team and help us discover and develop novel inhibitors of undruggable disease targets.
Your role will report to the Vice President of medical Development and will be to establish robust manufacturing processes for our drug substance. This will require both hands-on and strategic approaches, leveraging internal and external capabilities with high flexibility. Ideal candidates will be experienced, energetic, and passionate, with a broad knowledge of Process Chemistry / Chemical Development to influence and guide the best route
selection and development of our chemical processes. This position is primarily lab-based, and you will be a primary data generator with opportunities to lead a subteam of process chemists.
Leverage internal and external capabilities to advance our programs. Lead by example and take a hands-on approach to solving our most pressing challenges. Lead a subteam of 1-2 process chemists. Partner with early discovery through late stage development to discover and implement the best synthetic approaches to our Helicon TM peptides. Develop the best strategy for the synthesis of our Helicon TM peptides. What you'll need to be successful: Ph D with a minimum of 6-8+ years of industry experience in process chemistry.
Experience with development of safe, scalable processes and technology transfer to manufacturing sites. Hands-on experience with kilo-lab deliveries is a plus. Excellent communication, organization, strategic, and cross-functional team skills. Experience directly managing external vendors is a plus. Experience with Quality Assurance, Quality systems, and GMP production is a plus. Experience with regulatory filings is a plus. Synthetic experience with peptides is a plus. Able to work on-site and attend in-person meetings (Fog employees are required to be fully vaccinated to attend in-person work-related activities.
Reasonable Accommodations will be made for individuals with a sincerely held religious belief or disability who are not vaccinated) As an equal opportunity employer, Fog values diversity and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, interaction, interactionual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. 30 Acorn Park Drive - Cambridge, MA 02140 - #J-18808-Ljbffr
The optimal project outcome will see the new assay(s) implemented in Selux's second-generation AST platform in addition to publications. The successful candidate will work closely with Selux's senior scientists and engineers, have direct access to Selux's esteemed scientific and clinical advisors, and build industry and academic partnerships necessary to make the project successful.
We are looking for a candidate with experience working with bacteria and assay development, including use of time-resolved Forster resonance energy transfer (TR-FRET), fluorescence polarization/anisotropy. Selux Diagnostics' platforms will enable clinicians to administer personalized therapies to Infectious
Diseases patients within hours rather than days. These advances promise to improve patient care, shorten hospital stays, and combat the growing antibiotic resistance epidemic.
Selux's NGP AST platform offers uncompromised accuracy and an unprecedented speed to results and breadth of menu. The company's Grow-on-the-Go Blood Culture system completes the microbiology laboratory transformation by slashing the time to culture positivity for all samples and incubation during sample transport for integrated health networks. The 35-person company is funded with a combination of Federal and private investment and will begin FDA trials on its initial NGP AST product in this quarter (Q1-2020). The
ideal candidate will have/be: A Ph D in Microbiology, Biochemistry, Molecular Biology, Biomedical Engineering or a related field Experience performing phenotypic assays on bacteria Experience working with a variety of bacterial species Experience developing no-wash assays Experience performing TR-FRET and/or fluorescence polarization A desire to learn industrial R&D and see his/her work come to fruition in a product A desire to continue publishing An independent thinker and problem-solver, who is an enthusiastic and collaborative professional Excellent written and oral communication skills and proven ability to work well in a team environment Passion about an early-stage start-up that aims to change industry and how healthcare is delivered!
recblid 30k3bj2puip0ojss7rrj9os3kdftk0 Ph. D.
